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Acetylaconitine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Acetylaconitine
Price: $138 / 20mg
CAS No.: 77181-26-1
Catalog No.: CFN90261
Molecular Formula: C36H49NO12
Molecular Weight: 687.78 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Aconitum kusnezoffii Reichb.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $51.4 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 3-Acetylaconitine, aconitine, and deoxyaconitine are main toxic components of the roots of Aconitum pendulum.
Acetylaconitine Description
Source: The roots of Aconitum kusnezoffii Reichb.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.454 mL 7.2698 mL 14.5395 mL 29.0791 mL 36.3488 mL
5 mM 0.2908 mL 1.454 mL 2.9079 mL 5.8158 mL 7.2698 mL
10 mM 0.1454 mL 0.727 mL 1.454 mL 2.9079 mL 3.6349 mL
50 mM 0.0291 mL 0.1454 mL 0.2908 mL 0.5816 mL 0.727 mL
100 mM 0.0145 mL 0.0727 mL 0.1454 mL 0.2908 mL 0.3635 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2010 Mar;35(5):588-92.
Study on processing principle of Aconitum pendulum.[Pubmed: 20506817]
To study the processing principles of different processed products of Aconitum pendulum.
METHODS AND RESULTS:
Using high performance liquid chromatography and acute toxicity test to compare the changes in chemical composition and toxicity of the roots and processed products of A. pendulum. The main toxic components of the roots of A. pendulum were aconitine, deoxyaconitine and 3-Acetylaconitine. The contents of these three alkaloids were significantly reduced in processed products, while benzoylaconitine significantly increased. In addition, processed products emerged aconine, polyschistine-D, beyzoyldeoxyaconine, 16-epi-pyroaconitine and 16-epi-pyrodeoxyaconitine. From the structural analysis, these new emerged compounds transformed from the aconitine, deoxyaconitine and 3-Acetylaconitine.
CONCLUSIONS:
Different processing methods can reduce the toxicity of the roots of A. pendulum. Processing principle is ester hydrolysis and high-temperature pyrolysis.
Siamenoside I

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CAS No: 126105-12-2
Price: $338/20mg
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CAS No: 153-18-4
Price: $30/20mg
Verbasoside

Catalog No: CFN95015
CAS No: 61548-34-3
Price: $318/5mg
2-(3,4-Dihydroxyphenyl)ethanol

Catalog No: CFN99076
CAS No: 10597-60-1
Price: $88/20mg
Osthol

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CAS No: 484-12-8
Price: $30/20mg
Gallic acid

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CAS No: 149-91-7
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Benzoylhypacoitine

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Acetyleugenol

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Jaceosidin

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Price: $168/20mg
Nobiletin

Catalog No: CFN98726
CAS No: 478-01-3
Price: $30/20mg
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