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Acoforestinine
Acoforestinine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Acoforestinine
Price: $368 / 20mg
CAS No.: 110011-77-3
Catalog No.: CFN99502
Molecular Formula: C35H51NO10
Molecular Weight: 645.79 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: White powder
Source: The roots of Aconitum carmichaeli Debx.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $178.7 / In-stock
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Acoforestinine is a natural product from Aconitum handelianum.
Acoforestinine Description
Source: The roots of Aconitum carmichaeli Debx.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5485 mL 7.7425 mL 15.4849 mL 30.9698 mL 38.7123 mL
5 mM 0.3097 mL 1.5485 mL 3.097 mL 6.194 mL 7.7425 mL
10 mM 0.1548 mL 0.7742 mL 1.5485 mL 3.097 mL 3.8712 mL
50 mM 0.031 mL 0.1548 mL 0.3097 mL 0.6194 mL 0.7742 mL
100 mM 0.0155 mL 0.0774 mL 0.1548 mL 0.3097 mL 0.3871 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1927-9.
Diterpenoid alkaloids from Aconitum handelianum.[Pubmed: 19894536]
To investigate the alkaloids from Aconitum handelianum.
METHODS AND RESULTS:
The column chromatographic methods were employed for the isolation and purification of the chemical constituents. The structures were elucidated by spectroscopic methods. Eight diterpenoid alkaloids were isolated and identified as acoforine (1), Acoforestinine (2), 14-O-acetylsachaconitine (3), vilmorrianine C (4), vilmorrianine D (5), talatizamine (6), chasmanine (7) and yunaconitine (8).
CONCLUSIONS:
All compounds were isolated from this plant for the first time.
CFN90228Bullatine A1354-84-3343.51C22H33NO2
CFN93074Karacoline39089-30-0377.52C22H35NO4
CFN91495Guan-fu base A1394-48-5429.5C24H31NO6
CFN89550Delgrandine145237-05-4741.77C41H43NO12
CFN8954714-Dehydrodelcosine1361-18-8451.55C24H37NO7
CFN99502Acoforestinine110011-77-3645.79C35H51NO10
CFN893298-Deacetylyunaconitine93460-55-0617.73C33H47NO10
CFN99503Yunaconitine70578-24-4659.77C35H49NO11
CFN893623-Acetylyunaconitine80787-51-5701.80C37H51NO12
CFN99720Bulleyaconitine A107668-79-1643.8C35H49NO10
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