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Actinidic acid
Actinidic acid
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Product Name Actinidic acid
Price:
CAS No.: 341971-45-7
Catalog No.: CFN98444
Molecular Formula: C30H46O5
Molecular Weight: 486.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The leaves of Eucalyptus maideni
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Actinidic acid is a triterpene phytoalexin from unripe kiwi fruit.
In vitro:
Arch Pharm Res. 2008 May;31(5):666-70.
A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta.[Pubmed: 18481026]

METHODS AND RESULTS:
A new coumaroyl triterpene, 3-O-trans-p-coumaroyl Actinidic acid (1), as well as five known triterpenes, ursolic acid (2), 23-hydroxyursolic acid (3), corosolic acid (4), asiatic acid (5) and betulinic acid (6) were isolated from an EtOAc-soluble extract of the roots of Actinidia arguta. The structure of compound 1 was elucidated from interpretation of the spectroscopic data, particularly by extensive 1D and 2D NMR studies. All the isolates (1-6) were evaluated in vitro for their inhibitory activities on pancreatic lipase (PL).
CONCLUSIONS:
Of the isolates, the new compound 1 possessed the highest inhibitory activity on PL, with an IC(50) of 14.95 microM, followed by ursolic acid (2, IC(50) = 15.83 microM). The other four triterpenes (3-6) also showed significant PL inhibitory activity, with IC(50) values ranging from 20.42 to 76.45 microM.
Actinidic acid Description
Source: The leaves of Eucalyptus maideni
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0547 mL 10.2733 mL 20.5465 mL 41.0931 mL 51.3663 mL
5 mM 0.4109 mL 2.0547 mL 4.1093 mL 8.2186 mL 10.2733 mL
10 mM 0.2055 mL 1.0273 mL 2.0547 mL 4.1093 mL 5.1366 mL
50 mM 0.0411 mL 0.2055 mL 0.4109 mL 0.8219 mL 1.0273 mL
100 mM 0.0205 mL 0.1027 mL 0.2055 mL 0.4109 mL 0.5137 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Biosci Biotechnol Biochem. 2001 Feb;65(2):480-3.
Actinidic acid, a new triterpene phytoalexin from unripe kiwi fruit.[Pubmed: 11302196]

METHODS AND RESULTS:
Seven phytoalexins (1-7), including a new compound, were isolated from the peel of unripe kiwi fruit (Actinidia deliciosa cv. Golden King) that had been wounded and inoculated with Colletotrichum musae. The new phytoalexin (1) was identified as 2alpha,3beta,23-trihydroxy-12,20(30)-ursadien-28-oic acid, and named Actinidic acid.
CONCLUSIONS:
Phytoalexins 2-6 are known triterpenes but have not previously been described as phytoalexins. Phytoalexin 7 is the same triterpene as the phytoalexin of nectarine fruit.
CFN99059Esculentic acid103974-74-9488.7 C30H48O5
CFN98444Actinidic acid341971-45-7486.7 C30H46O5
CFN98688Asiatic acid464-92-6488.7 C30H48O5
CFN968303-O-Coumaroylasiatic acid143773-52-8634.85C39H54O7
CFN99912Asiaticoside16830-15-2959.12C48H78O19
CFN99913Madecassoside34540-22-2975.13C48H78O20
CFN95124Asiaticoside B125265-68-1975.13C48H78O20
CFN99914Madecassic acid18449-41-7504.70C30H48O6
CFN994812,24-Dihydroxyursolic acid143839-02-5488.7 C30H48O5
CFN96162Barbinervic acid64199-78-6488.7C30H48O5
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