Actinidic acid | CAS:341971-45-7 | Manufacturer ChemFaces

Actinidic acid

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Description:

Actinidic acid is a triterpene phytoalexin from unripe kiwi fruit.

In vitro:

Arch Pharm Res. 2008 May;31(5):666-70.

A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta.[Pubmed: 18481026]

METHODS AND RESULTS:
A new coumaroyl triterpene, 3-O-trans-p-coumaroyl Actinidic acid (1), as well as five known triterpenes, ursolic acid (2), 23-hydroxyursolic acid (3), corosolic acid (4), asiatic acid (5) and betulinic acid (6) were isolated from an EtOAc-soluble extract of the roots of Actinidia arguta. The structure of compound 1 was elucidated from interpretation of the spectroscopic data, particularly by extensive 1D and 2D NMR studies. All the isolates (1-6) were evaluated in vitro for their inhibitory activities on pancreatic lipase (PL).
CONCLUSIONS:
Of the isolates, the new compound 1 possessed the highest inhibitory activity on PL, with an IC(50) of 14.95 microM, followed by ursolic acid (2, IC(50) = 15.83 microM). The other four triterpenes (3-6) also showed significant PL inhibitory activity, with IC(50) values ranging from 20.42 to 76.45 microM.

Actinidic acid Description

Source:	The leaves of Eucalyptus maideni
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Actinidic acid
Price:
CAS No.:	341971-45-7
Catalog No.:	CFN98444
Molecular Formula:	C₃₀H₄₆O₅
Molecular Weight:	486.7 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The leaves of Eucalyptus maideni
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phytoalexin Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.0547 mL	10.2733 mL	20.5465 mL	41.0931 mL	51.3663 mL
5 mM	0.4109 mL	2.0547 mL	4.1093 mL	8.2186 mL	10.2733 mL
10 mM	0.2055 mL	1.0273 mL	2.0547 mL	4.1093 mL	5.1366 mL
50 mM	0.0411 mL	0.2055 mL	0.4109 mL	0.8219 mL	1.0273 mL
100 mM	0.0205 mL	0.1027 mL	0.2055 mL	0.4109 mL	0.5137 mL

CFN99481	2,24-Dihydroxyursolic acid	143839-02-5	488.7	C₃₀H₄₈O₅
CFN96162	Barbinervic acid	64199-78-6	488.7	C₃₀H₄₈O₅
CFN96828	Myrianthic acid	89786-84-5	504.70	C₃₀H₄₈O₆
CFN91072	19 alpha-Hydroxyasiatic acid	70868-78-9	504.7	C₃₀H₄₈O₆
CFN89232	Myrianthic acid 3,23-acetonide	578710-52-8	544.77	C₃₃H₅₂O₆
CFN99059	Esculentic acid	103974-74-9	488.7	C₃₀H₄₈O₅
CFN98444	Actinidic acid	341971-45-7	486.7	C₃₀H₄₆O₅
CFN95960	2alpha,3beta,23-trihydroxyurs-20-en-28-oic acid	948827-08-5	488.7	C₃₀H₄₈O₅
CFN98688	Asiatic acid	464-92-6	488.7	C₃₀H₄₈O₅
CFN96830	3-O-Coumaroylasiatic acid	143773-52-8	634.85	C₃₉H₅₄O₇