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Angelic acid
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Product Name Angelic acid
Price: $40 / 20mg
CAS No.: 565-63-9
Catalog No.: CFN92466
Molecular Formula: C5H8O2
Molecular Weight: 100.1 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Powder
Source: The roots of Angelica sinensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Angelic acid is a monocarboxylic unsaturated organic acid, which is useful as perfume materials.
In vitro:
Volume 18, Issue 10, 17 September 1979, Pages 1647-1649
The biosynthesis of angelic acid in Cynoglossum officinale[Reference: WebLink]

METHODS AND RESULTS:
Six-month-old Cynoglossum officinale plants were fed via the roots with tiglic acid-[1-14C]. After a week the plants were harvested, the alkaloid heliosupine was isolated and hydrolysed to heliotridine and Angelic acid. <
CONCLUSIONS:
The latter contained all the radioactivity of the original heliosupine showing that Angelic acid may be formed from tiglic acid by a cis-trans isomerization.
Angelic acid Description
Source: The roots of Angelica sinensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 9.99 mL 49.95 mL 99.9001 mL 199.8002 mL 249.7502 mL
5 mM 1.998 mL 9.99 mL 19.98 mL 39.96 mL 49.95 mL
10 mM 0.999 mL 4.995 mL 9.99 mL 19.98 mL 24.975 mL
50 mM 0.1998 mL 0.999 mL 1.998 mL 3.996 mL 4.995 mL
100 mM 0.0999 mL 0.4995 mL 0.999 mL 1.998 mL 2.4975 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
US 4613680 A[P]. 1986.
PROCESS FOR PREPARING ANGELIC ACID OR ITS ESTER[Reference: WebLink]
Angelic acid or esters thereof which are useful as perfume materials are prepared by isomerizing tiglic acid or an ester thereof with an organic sulfinic acid as the catalyst, and novel esters of Angelic acid represented by the formula wherein R represents 3-hexenyl, 3-methyl-2-butenyl, 3-methyl-3-butenyl, 3-methyl-2-pentenyl, 3-methyl-4-pentenyl, CH3(CH2)l- (in which l is an integer from 5 to 9), cyclopentyl, cyclohexyl, 2-methylpentyl, alpha -methylbenzyl, neryl or furfuryl are provided as part of said esters of Angelic acid.
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Gancaonin N

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