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Angelol K
Angelol K
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Angelol K
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CAS No.: 169736-93-0
Catalog No.: CFN80136
Molecular Formula: C20H24O7
Molecular Weight: 376.15 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The roots of Angelica sinensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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  • Gyeongsang National University (Korea)
  • University of Medicine and Phar... (Romania)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Angelol K shows significant activity on human platelet aggregation.
In vitro:
Phytochemistry. 1995 Jul;39(5):1099-101.
Angelol-type coumarins from Angelica pubescence F. biserrata and their inhibitory effect on platelet aggregation.[Pubmed: 7662273]

METHODS AND RESULTS:
An ethyl acetate-soluble root extract of Angelica pubescence f. biserrata afforded two new angelol-type coumarins, Angelol K and angelol L, in addition to angelol B, angelol C, angelol D and angelol G.
CONCLUSIONS:
Some of the compounds were tested on human platelet aggregation and showed significant activity.
Angelol K Description
Source: The roots of Angelica sinensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6585 mL 13.2926 mL 26.5851 mL 53.1703 mL 66.4628 mL
5 mM 0.5317 mL 2.6585 mL 5.317 mL 10.6341 mL 13.2926 mL
10 mM 0.2659 mL 1.3293 mL 2.6585 mL 5.317 mL 6.6463 mL
50 mM 0.0532 mL 0.2659 mL 0.5317 mL 1.0634 mL 1.3293 mL
100 mM 0.0266 mL 0.1329 mL 0.2659 mL 0.5317 mL 0.6646 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN91925Angelol H83247-73-8376.40C20H24O7
CFN92733Toddaculine4335-12-0274.3C16H18O4
CFN90247Toddalolactone483-90-9308.33C16H20O6
CFN95372Toddalolactone 3'-O-methyl ether (6-(2-Hydroxy-3-methoxy-3-methylbutyl)-5,7-dimethoxycoumarin)143614-35-1322.4C17H22O6
CFN92513(-)-Toddanol77715-99-2290.3C16H18O5
CFN92514Toddanone77636-08-9290.3C16H18O5
CFN927325-Methoxysuberenone85011-58-1274.3C15H14O5
CFN98985Suberosin581-31-7244.3 C15H16O3
CFN89248Dehydrogeijerin16850-91-2258.27C15H14O4
CFN89250Hopeyhopin63975-56-4274.27C15H14O5
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