Angophorol | CAS:133442-54-3 | Manufacturer ChemFaces

Angophorol

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Angophorol exerts potential anticancer activity through growth inhibition and apoptosis in K562 cells.

In vitro:

Planta Medica, 2013,79 (5):55.

Therapeutic Efficacy of Phenolic Compounds from Micnia prasina. in Acute Lymphoblastic Leukemia.[Reference: WebLink]

METHODS AND RESULTS:
Three flavonones A, B, and C, were isolated from the leaves and stem of Miconia prasina. The flavonones were characterized structurally as (-)-farrerol (A), Angophorol (B) and desmethoxymatteucinol (C), respectively. Their structures were elucidated by spectroscopic analysis including HRMS, 1D, and 2D NMR. The anti-leukemia effect of the flavonones constituents of the Miconia prasina leaves was also examined in vitro, where the result showed that flavonones A, B and C exert potential anticancer activity through growth inhibition and apoptosis in K562 cells.
CONCLUSIONS:
This is the first report for these compounds being isolated from Miconia prasina, and it is the first time to measure their anti-leukemia activity against two human leukemia cell lines, HL60 and K562, after a 48h exposure.

Angophorol Description

Source:	The barks of Cephalotaxus sinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Angophorol
Price:
CAS No.:	133442-54-3
Catalog No.:	CFN96057
Molecular Formula:	C₁₈H₁₈O₅
Molecular Weight:	314.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The barks of Cephalotaxus sinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anticancer Compound Library Pro-apoptotic Compound Library Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1817 mL	15.9084 mL	31.8167 mL	63.6335 mL	79.5418 mL
5 mM	0.6363 mL	3.1817 mL	6.3633 mL	12.7267 mL	15.9084 mL
10 mM	0.3182 mL	1.5908 mL	3.1817 mL	6.3633 mL	7.9542 mL
50 mM	0.0636 mL	0.3182 mL	0.6363 mL	1.2727 mL	1.5908 mL
100 mM	0.0318 mL	0.1591 mL	0.3182 mL	0.6363 mL	0.7954 mL

CFN90711	5,7,4'-Trihydroxy-8-methylflavanone	916917-28-7	286.08	C₁₆H₁₄O₅
CFN96502	Poriol	14348-16-4	286.28	C₁₆H₁₄O₅
CFN96038	7-O-Methylporiol	206560-99-8	300.3	C₁₇H₁₆O₅
CFN90337	Farrerol	24211-30-1	300.3	C₁₇H₁₆O₅
CFN96057	Angophorol	133442-54-3	314.3	C₁₈H₁₈O₅
CFN96548	6-Methyl-8-prenylnaringenin	261776-60-7	354.40	C₂₁H₂₂O₅