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Apoatropine
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Product Name Apoatropine
Price:
CAS No.: 500-55-0
Catalog No.: CFN00149
Molecular Formula: C17H21NO2
Molecular Weight: 271.36 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Atropa belladonna L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
J Chromatogr A. 2005 Oct 14;1091(1-2):32-9.
Simultaneous analysis of hyoscyamine, scopolamine, 6beta-hydroxyhyoscyamine and apoatropine in Solanaceous hairy roots by reversed-phase high-performance liquid chromatography.[Pubmed: 16395790]

METHODS AND RESULTS:
A new high-performance liquid chromatographic method is described for tropane alkaloid analysis in genetically transformed root cultures of Datura innoxia Mill. and Atropa belladonna L. Sample preparation, tropane alkaloid extraction with chloroform-methanol-concentrated ammonia 15:5:1 (v/v/v), was followed by solid-phase extraction on Supelclean LC-18 cartridges. Optimized conditions and careful pH control resulted in high recovery and reproducibility. Simultaneous determination of Apoatropine, 6beta-hydroxyhyoscyamine, hyoscyamine and scopolamine was performed by HPLC on C18 (2) reversed-phase column. The application of Luna new-generation silica-based stationary phase resulted in excellent peak shapes using an ion-pair reagent and triethanolamine free mobile phase and allowed to exploit the full power of pH-dependent selectivity.
CONCLUSIONS:
Simplicity and improved selectivity make this method a preferred alternative of published ion-pair chromatographic methods. Validation studies proved that the global method has good repeatability and satisfactory recovery. Absolute limits of detection were 0.6, 0.6, and 0.8 ng for hyoscyamine, 6beta-hydroxyhyoscyamine, and scopolamine respectively.
Apoatropine Description
Source: The herbs of Atropa belladonna L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

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Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6851 mL 18.4257 mL 36.8514 mL 73.7028 mL 92.1285 mL
5 mM 0.737 mL 3.6851 mL 7.3703 mL 14.7406 mL 18.4257 mL
10 mM 0.3685 mL 1.8426 mL 3.6851 mL 7.3703 mL 9.2129 mL
50 mM 0.0737 mL 0.3685 mL 0.737 mL 1.4741 mL 1.8426 mL
100 mM 0.0369 mL 0.1843 mL 0.3685 mL 0.737 mL 0.9213 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Gartanin

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CAS No: 33390-42-0
Price: $318/5mg
Luteolin-4'-O-glucoside

Catalog No: CFN93776
CAS No: 6920-38-3
Price: $ / mg
Cinnamaldehyde

Catalog No: CFN99478
CAS No: 104-55-2
Price: $30/20mg
Brevilin A

Catalog No: CFN99694
CAS No: 16503-32-5
Price: $128/20mg
Pseudoprotodioscin

Catalog No: CFN90694
CAS No: 102115-79-7
Price: $138/20mg
Nodakenin

Catalog No: CFN90232
CAS No: 495-31-8
Price: $70/20mg
N-p-trans-Coumaroyltyramine

Catalog No: CFN98494
CAS No: 36417-86-4
Price: $268/10mg
Baicalein

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Price: $40/20mg
Ligustilide

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Price: $70/20mg
Cauloside A

Catalog No: CFN96440
CAS No: 17184-21-3
Price: $318/10mg
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