Atractyloside potassium salt | CAS:102130-43-8

Atractyloside potassium salt

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Description:

Atractyloside potassium salt inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane.

In vitro:

Planta Med . 2015 Aug;81(12-13):1213-20.

Influence of Processing on the Content of Toxic Carboxyatractyloside and Atractyloside and the Microbiological Status of Xanthium sibiricum Fruits (Cang'erzi)[Pubmed: 26287695]

Abstract The dried ripe fruits of Xanthium sibiricum (Cang'erzi) are used in traditional Chinese medicine for the treatment of nasal congestion, nasal discharge, allergic rhinitis, sinusitis, and wind-cold headaches. Carboxyatractyloside and atractyloside are important constituents of the fruits because these diterpenoid glycosides are responsible for their toxicity. In order to evaluate procedures for reducing the amount of the more toxic carboxyatractyloside, the fruits were dried and heated with different methods. Carboxyatractyloside and atractyloside were analysed by a new reversed-phase high-performance liquid chromatographic method using liquid chromatography-diode array detector-tandem mass spectrometry analysis. The results revealed that temperature and drying methods have a strong influence on the content of carboxyatractyloside and atractyloside. Fruits which were treated at higher temperatures showed a lower content of carboxyatractyloside and an increased content of atractyloside, which is 50 times less toxic. This indicates that the roasting process can reduce toxicity effectively. The microbiological colonisation of Xanthium fruits is also reduced by roasting and by drying above 100 °C. For the safe use of Cang'erzi, the effect of processing should be monitored and analysis of carboxyatractyloside and atractyloside should be obligatory in quality control.

Atractyloside potassium salt Description

Source:	The herbs of Atractylis gummifera
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Atractyloside potassium salt
Price:	$138 / 20mg
CAS No.:	102130-43-8
Catalog No.:	CFN98561
Molecular Formula:	C₃₀H₄₄K₂O₁₆S₂
Molecular Weight:	802.99 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The herbs of Atractylis gummifera
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cardioprotective Compound Library Toxicity Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.2453 mL	6.2267 mL	12.4535 mL	24.9069 mL	31.1336 mL
5 mM	0.2491 mL	1.2453 mL	2.4907 mL	4.9814 mL	6.2267 mL
10 mM	0.1245 mL	0.6227 mL	1.2453 mL	2.4907 mL	3.1134 mL
50 mM	0.0249 mL	0.1245 mL	0.2491 mL	0.4981 mL	0.6227 mL
100 mM	0.0125 mL	0.0623 mL	0.1245 mL	0.2491 mL	0.3113 mL

CFN90984	Rebaudioside G	127345-21-5	804.87	C₃₈H₆₀O₁₈
CFN99548	Stevioside	57817-89-7	804.88	C₃₈H₆₀O₁₈
CFN95215	Rebaudioside F	438045-89-7	937.0	C₄₃H₆₈O₂₂
CFN99110	Rebaudioside A	58543-16-1	967.01	C₄₄H₇₀O₂₃
CFN90258	Rebaudioside C	63550-99-2	951.02	C₄₄H₇₀O₂₂
CFN95229	Stevia impurity (13-[(2-O-6-deoxy-beta-D-glucopyranosyl-3-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid beta-D-glucopyranosyl ester)	1309929-72-3	951.0	C₄₄H₇₀O₂₂
CFN90257	Rebaudioside D	63279-13-0	1129.15	C₅₀H₈₀O₂₈
CFN91096	Rebaudioside E	63279-14-1	967.02	C₄₄H₇₀O₂₃
CFN91167	Rebaudioside N	1220616-46-5	1275.9	C₅₆H₉₀O₃₂
CFN70259	Rebaudioside M	1220616-44-3	1291.3	C₅₆H₉₀O₃₃