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Clausine I
Clausine I
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Clausine I
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CAS No.: 182261-94-5
Catalog No.: CFN97800
Molecular Formula: C14H11NO3
Molecular Weight: 241.24 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Yellow powder
Source: The herbs of Clausena excavata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Clausine I Description
Source: The herbs of Clausena excavata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.1452 mL 20.7262 mL 41.4525 mL 82.905 mL 103.6312 mL
5 mM 0.829 mL 4.1452 mL 8.2905 mL 16.581 mL 20.7262 mL
10 mM 0.4145 mL 2.0726 mL 4.1452 mL 8.2905 mL 10.3631 mL
50 mM 0.0829 mL 0.4145 mL 0.829 mL 1.6581 mL 2.0726 mL
100 mM 0.0415 mL 0.2073 mL 0.4145 mL 0.829 mL 1.0363 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron, 2012, 68(33):6727---6736.
Transition metals in organic synthesis. Part 101: Convergent total synthesis of 1,6-dioxygenated carbazole alkaloids.[Reference: WebLink]

METHODS AND RESULTS:
Using a palladium(II)-catalysed oxidative cyclisation as key step, we describe a highly efficient total synthesis of a series of naturally occurring 1,6-dioxygenated carbazole alkaloids: clausenine, 6-methoxymurrayanine, clausenol, clausine G, Clausine I, clausine Z and methyl 1,6-dihydroxy-9H-carbazole-3-carboxylate.
CFN97796Clauszoline M187110-72-1227.22C13H9NO3
CFN92926Curryangine25488-37-3331.45C23H25NO
CFN92927Murrayamine E172617-68-4347.45C23H25NO2
CFN91189Koenimbine21087-98-9293.4C19H19NO2
CFN70319Koenigicine24123-92-0323.4C20H21NO3
CFN92197Mahanimbine21104-28-9331.5C23H25NO
CFN92198Isomahanimbine26871-46-5331.5C23H25NO
CFN92199Mahanine28360-49-8347.5C23H25NO2
CFN92200Isomahanine144606-95-1347.5C23H25NO2
CFN92201Murrayanol144525-81-5363.5C24H29NO2
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