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Consiculine
Consiculine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Consiculine
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CAS No.: 219829-73-9
Catalog No.: CFN00185
Molecular Formula: C20H29NO5
Molecular Weight: 363.45 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Convolvulus siculus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Consiculine is a natural product from Convolvulus siculus.
Consiculine Description
Source: The roots of Convolvulus siculus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7514 mL 13.7571 mL 27.5141 mL 55.0282 mL 68.7853 mL
5 mM 0.5503 mL 2.7514 mL 5.5028 mL 11.0056 mL 13.7571 mL
10 mM 0.2751 mL 1.3757 mL 2.7514 mL 5.5028 mL 6.8785 mL
50 mM 0.055 mL 0.2751 mL 0.5503 mL 1.1006 mL 1.3757 mL
100 mM 0.0275 mL 0.1376 mL 0.2751 mL 0.5503 mL 0.6879 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry , 1998 , 49 (5) :1449-51.
Tropane alkaloids with a unique type of acyl moiety from two convolvulus species fn1[Reference: WebLink]
An investigation of the roots of Convolvulus siculus and C. sabatius ssp. mauritanicus afforded two new tropan-3α-ol esters named Consiculine and consabatine and the known base merresectine B (3). The acyl residues of the new alkaloids are formed by consiculic acid ( = 1β,2α-dihydroxy-5-prenyl-cyclohex-5-en-4-one carboxylic acid) and its 2-deoxy derivative, respectively.
CFN00174Belladonnine510-25-8542.72C34H42N2O4
CFN00175Beta-Belladonnine6696-63-5542.72C34H42N2O4
CFN00176Alpha-Belladonnine5878-33-1542.72C34H42N2O4
CFN00185Consiculine219829-73-9363.45C20H29NO5
CFN00200Littorine21956-47-8289.37C17H23NO3
CFN00201Merresectine B219829-75-1559.70C31H45NO8
CFN002021-Hydroxytropacocaine156497-23-3261.32C15H19NO3
CFN00211Tropanyl phenylacetate1690-22-8259.35C16H21NO2
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