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Cyclo(L-Leu-trans-4-hydroxy-L-Pro)
Cyclo(L-Leu-trans-4-hydroxy-L-Pro)
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Cyclo(L-Leu-trans-4-hydroxy-L-Pro)
Price: $238 / 10mg
CAS No.: 115006-86-5
Catalog No.: CFN96088
Molecular Formula: C11H18N2O3
Molecular Weight: 226.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: From Phellinus igniarius
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Cyclo(L-Leu-trans-4-hydroxy-L-Pro) is a natural product from Phellinus igniarius.
Cyclo(L-Leu-trans-4-hydroxy-L-Pro) Description
Source: From Phellinus igniarius
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4189 mL 22.0946 mL 44.1891 mL 88.3783 mL 110.4728 mL
5 mM 0.8838 mL 4.4189 mL 8.8378 mL 17.6757 mL 22.0946 mL
10 mM 0.4419 mL 2.2095 mL 4.4189 mL 8.8378 mL 11.0473 mL
50 mM 0.0884 mL 0.4419 mL 0.8838 mL 1.7676 mL 2.2095 mL
100 mM 0.0442 mL 0.2209 mL 0.4419 mL 0.8838 mL 1.1047 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemical Research & Application, 2014 (9) :1478-1482.
Cyclic dipeptides metabolites from the symbiotic fungus paraconiothyrium brasiliense[Reference: WebLink]
Nine cyclic dipeptides secondary metabolites were isolated from the symbiotic fungus paraconiothyrium brasiliense,by normal phase silica gel,Sephadex LH-20 chromatography and reverse phase HPLC.
METHODS AND RESULTS:
Their structures were elucidated as cyclo-( LLeu-L-Tyr)(1),cyclo-(L-Trp-L-Pro)(2),cyclo-( L-Pro-L-Phe)(3),cyclo-( L-Pro-L-Tyr)(4),cyclo-( L-Pro-L-Leu)(5),Cyclo(L-Leu-trans-4-hydroxy-L-Pro)(6),cyclo-(L-Ile-L-Pro)(7),cyclo-(L-Val-L-Pro)(8),cyclo-(L-Leu-L-Ile)(9)by NMR,MS and physicochemical properties.
CONCLUSIONS:
All the compounds were isolated from the symbiotic fungus paraconiothyrium brasiliense for the first time.
Delta 7-avenasterol

Catalog No: CFN92240
CAS No: 23290-26-8
Price: $ / mg
Nuciferine

Catalog No: CFN99733
CAS No: 475-83-2
Price: $40/20mg
Epimedin B

Catalog No: CFN99940
CAS No: 110623-73-9
Price: $128/20mg
Protopine

Catalog No: CFN99399
CAS No: 130-86-9
Price: $50/20mg
Clematichinenoside AR

Catalog No: CFN93289
CAS No: 761425-93-8
Price: $238/10mg
2-Amino-3-carboxy-1,4-naphthoquinone

Catalog No: CFN91040
CAS No: 173043-38-4
Price: $388/5mg
Isovitexin

Catalog No: CFN98620
CAS No: 38953-85-4
Price: $50/20mg
1,5-Dicaffeoylquinic acid

Catalog No: CFN90937
CAS No: 19870-46-3
Price: $138/20mg
Lotusine

Catalog No: CFN93034
CAS No: 6871-67-6
Price: $218/10mg
Diosbulbin B

Catalog No: CFN98014
CAS No: 20086-06-0
Price: $80/20mg
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