Cyclo(Phe-Leu) | CAS:3354-31-2 | Manufacturer ChemFaces

Cyclo(Phe-Leu)

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Product Name	Cyclo(Phe-Leu)
Price:	$238 / 10mg
CAS No.:	3354-31-2
Catalog No.:	CFN90273
Molecular Formula:	C₁₅H₂₀N₂O₂
Molecular Weight:	260.34 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The roots of Rubia schumanniana Pritzel
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $99.2 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Cyclo(Phe-Leu) is a new cell cycle inhibitor.

In vitro:

Journal of Shenyang Pharmaceutical University, 2015 (2):107 -10.

Cyclic dipeptides as new cell cycle inhibitors produced by Streptomyces flavoretus 18522[Reference: WebLink]

To find the cell cycle inhibitors from the metabolites of Streptomyces flavoretus 18522.
METHODS AND RESULTS:
Activity-guided isolation was performed on the chloroform extract of the fermentation broth and mycelia of Streptomyces flavoretus 18522 by using ts FT210 cells.Compounds were isolated through various chromatoghraphic methods and elucidated by spectroscopic means.The flow cytometry was used to evaluate the cell cycle inhibiting activity of the fractions and compounds. Six cyclic dipeptides were obtained and identified as cyclo(Ala-Leu)(1),Cyclo(Ile-Ala)(2),cyclo(Ala-Val)(3),Cyclo(Phe-Leu)(4),cyclo(Ala-Pro)(5) and cyclo(Phe-Val)(6).Conclusions Compounds 1-6 are reported as new cell cycle inhibitors for the first time.

Cyclo(Phe-Leu) Description

Source:	The roots of Rubia schumanniana Pritzel
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Anti-mitotic Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.8411 mL	19.2057 mL	38.4113 mL	76.8226 mL	96.0283 mL
5 mM	0.7682 mL	3.8411 mL	7.6823 mL	15.3645 mL	19.2057 mL
10 mM	0.3841 mL	1.9206 mL	3.8411 mL	7.6823 mL	9.6028 mL
50 mM	0.0768 mL	0.3841 mL	0.7682 mL	1.5365 mL	1.9206 mL
100 mM	0.0384 mL	0.1921 mL	0.3841 mL	0.7682 mL	0.9603 mL

CFN90286	Cyclo(Phe-Gly)	5037-75-2	204.23	C₁₁H₁₂N₂O₂
CFN90269	Cyclo(Tyr-Gly)	5625-49-0	220.22	C₁₁H₁₂N₂O₃
CFN90266	Cyclo(Ala-Phe)	14474-78-3	218.26	C₁₂H₁₄N₂O₂
CFN90267	Cyclo(Ala-Tyr)	21754-26-7	234.25	C₁₂H₁₄N₂O₃
CFN90274	Cyclo(Phe-Val)	14474-71-6	246.31	C₁₄H₁₈N₂O₂
CFN90268	Cyclo(Tyr-Val)	21754-25-6	262.30	C₁₄H₁₈N₂O₃
CFN90273	Cyclo(Phe-Leu)	3354-31-2	260.34	C₁₅H₂₀N₂O₂
CFN90287	Cyclo(Tyr-Leu)	82863-65-8	276.33	C₁₅H₂₀N₂O₃
CFN91446	Albonoursin	1222-90-8	256.3	C₁₅H₁₆N₂O₂