Science | Nature | Cell | View More
Natural Products
Dehydrobruceantin
Dehydrobruceantin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Dehydrobruceantin
Price:
CAS No.: 53662-98-9
Catalog No.: CFN89337
Molecular Formula: C28H34O11
Molecular Weight: 546.56 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The seeds of Brucea javanica (L.) Merr.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Tohoku University (Japan)
  • Griffith University (Australia)
  • University of Oslo (Norway)
  • Georgia Institute of Technology (USA)
  • Universiti Sains Malaysia (Malaysia)
  • University of Zurich (Switzerland)
  • China Medical University (Taiwan)
  • Korea Food Research Institute(K... (Korea)
  • Universidad de Antioquia (Colombia)
  • University of Brasilia (Brazil)
  • Shanghai University of TCM (China)
  • More...
Package
Featured Products
3,9-Dihydroxypterocarpan

Catalog No: CFN97043
CAS No: 61135-91-9
Price: $ /
Carnosol

Catalog No: CFN99956
CAS No: 5957-80-2
Price: $80/20mg
Quassin

Catalog No: CFN97246
CAS No: 76-78-8
Price: $338/5mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
Chebulagic acid

Catalog No: CFN92295
CAS No: 23094-71-5
Price: $ / mg
Seneciphylline

Catalog No: CFN98747
CAS No: 480-81-9
Price: $238/5mg
Sinensetin

Catalog No: CFN99599
CAS No: 2306-27-6
Price: $100/20mg
Soyasaponin Ab

Catalog No: CFN90773
CAS No: 118194-13-1
Price: $ / mg
Senkyunolide A

Catalog No: CFN99594
CAS No: 62006-39-7
Price: $90/20mg
Gallocatechin gallate

Catalog No: CFN96488
CAS No: 5127-64-0
Price: $100/5mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Dehydrobruceantin has anti-tuberculosis activity.
Targets: Antifection
In vitro:
Chem Pharm Bull (Tokyo). 1997 Sep;45(9):1527-9.
Anti-tuberculosis activity of quassinoids.[Pubmed: 9332005]

METHODS AND RESULTS:
In vitro evaluation of anti-tuberculosis activity was conducted for fifty-six quassinoids isolated in our laboratory from Simaroubaceous plants, Ailanthus altissima (= Aa, 10 compounds), Brucea antidysenterica (= Ba, 16 compounds), Picrasma ailanthoides (= Pa, 14 compounds), and Brucea javanica (= Bj, 16 compounds).
CONCLUSIONS:
Of the compounds tested, shinjulactone K (1), ailanthone (2), shinjudilactone (3), and Dehydrobruceantin (4) were the most potent. Although the activities were very low (0-19%), the resulting data provided a picture of structure-activity relationships.
Dehydrobruceantin Description
Source: The seeds of Brucea javanica (L.) Merr.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
1,3,4,6-Tetragalloylglucose

Catalog No: CFN95425
CAS No: 26922-99-6
Price: $318/10mg
Leachianol F

Catalog No: CFN95147
CAS No: 164123-50-6
Price: $318/5mg
Nortrachelogenin-8'-O-beta-glucosi...

Catalog No: CFN95234
CAS No: 858127-38-5
Price: $368/10mg
19-O-beta-D-carboxyglucopyranosyl-...

Catalog No: CFN95217
CAS No: 1011714-20-7
Price: $318/5mg
Leachianol G

Catalog No: CFN95146
CAS No: 164204-62-0
Price: $368/5mg
Caraganaphenol A

Catalog No: CFN95093
CAS No: 174916-31-5
Price: $333/5mg
Sophoraflavone A

Catalog No: CFN95510
CAS No: 105594-08-9
Price: $318/10mg
6-Methoxyfraxinellone

Catalog No: CFN95485
CAS No: N/A
Price: $318/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8296 mL 9.1481 mL 18.2963 mL 36.5925 mL 45.7406 mL
5 mM 0.3659 mL 1.8296 mL 3.6593 mL 7.3185 mL 9.1481 mL
10 mM 0.183 mL 0.9148 mL 1.8296 mL 3.6593 mL 4.5741 mL
50 mM 0.0366 mL 0.183 mL 0.3659 mL 0.7319 mL 0.9148 mL
100 mM 0.0183 mL 0.0915 mL 0.183 mL 0.3659 mL 0.4574 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J. Org. Chem.,1975,40(5):648–654.
The isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica[Reference: WebLink]

METHODS AND RESULTS:
The isolation and structural elucidation of the new potent antileukemic principles, bruceantin (1) and bruceantinol (3), and the new companion quassinoids, bruceantarin (2), Dehydrobruceantin (8), dehydrobruceantarin (9), dehydrobruceine B (10), dehydrobruceantol (11), and isobruceine B (12), are reported. Bruceantin (1), bruceantinol (3), and bruceantarin (2) were shown by hydrolysis to be trans-3,4-dimethyl-2-pentenoate, trans-4-hydroxy-3,4-dimethyl-2-pentenoate, and benzoate esters, respectively, of bruceolide (5).
CONCLUSIONS:
The dehydro compounds were shown to have a 2-hydroxy-3-keto-4-methylcyclohexa-1,4-diene A ring, a feature new to the quassinoids. Isobruceine B (12) was shown to be an A-ring isomer of the known bruceine B (4).
3,9-Dihydroxypterocarpan

Catalog No: CFN97043
CAS No: 61135-91-9
Price: $ /
Carnosol

Catalog No: CFN99956
CAS No: 5957-80-2
Price: $80/20mg
Quassin

Catalog No: CFN97246
CAS No: 76-78-8
Price: $338/5mg
Trilobatin

Catalog No: CFN98658
CAS No: 4192-90-9
Price: $30/20mg
Chebulagic acid

Catalog No: CFN92295
CAS No: 23094-71-5
Price: $ / mg
Seneciphylline

Catalog No: CFN98747
CAS No: 480-81-9
Price: $238/5mg
Sinensetin

Catalog No: CFN99599
CAS No: 2306-27-6
Price: $100/20mg
Soyasaponin Ab

Catalog No: CFN90773
CAS No: 118194-13-1
Price: $ / mg
Senkyunolide A

Catalog No: CFN99594
CAS No: 62006-39-7
Price: $90/20mg
Gallocatechin gallate

Catalog No: CFN96488
CAS No: 5127-64-0
Price: $100/5mg
Tags: buy Dehydrobruceantin | Dehydrobruceantin supplier | purchase Dehydrobruceantin | Dehydrobruceantin cost | Dehydrobruceantin manufacturer | order Dehydrobruceantin | Dehydrobruceantin distributor