Dehydroheliobuphthalmin | CAS:103001-05-4

Dehydroheliobuphthalmin

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Description:

Dehydroheliobuphthalmin has significant neuroprotective activities against glutamate- induced neurotoxicity.

In vitro:

Nat. Prod. Sci.,2008,14(3):167-70.

Neuroprotective lignans from Biota orientalis leaves.[Reference: WebLink]

METHODS AND RESULTS:
We previously reported that 90% MeOH fraction of Biota orientalis leaves (L.) ENDL. had significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells. In the present study, (-)-savinin (1), (-)-hinokinin (2), Dehydroheliobuphthalmin (3) were isolated by bioactivity-guided fractionation from the 90% MeOH fraction.
CONCLUSIONS:
All three lignans had significant neuroprotective activities against glutamate-induced neurotoxicity at the concentrations ranging from 0.1 to 10.0 μM.

Dehydroheliobuphthalmin Description

Source:	The leaves of Platycladus orientalis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Dehydroheliobuphthalmin
Price:
CAS No.:	103001-05-4
Catalog No.:	CFN99046
Molecular Formula:	C₂₂H₂₀O₈
Molecular Weight:	412.4 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The leaves of Platycladus orientalis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Neuroprotection Compound Library Lignans Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.4248 mL	12.1242 mL	24.2483 mL	48.4966 mL	60.6208 mL
5 mM	0.485 mL	2.4248 mL	4.8497 mL	9.6993 mL	12.1242 mL
10 mM	0.2425 mL	1.2124 mL	2.4248 mL	4.8497 mL	6.0621 mL
50 mM	0.0485 mL	0.2425 mL	0.485 mL	0.9699 mL	1.2124 mL
100 mM	0.0242 mL	0.1212 mL	0.2425 mL	0.485 mL	0.6062 mL

CFN96694	Pregomisin	66280-26-0	390.47	C₂₂H₃₀O₆
CFN89236	Anhydrosecoisolariciresinol	29388-33-8	344.40	C₂₀H₂₄O₅
CFN96711	4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan	1206464-65-4	374.43	C₂₁H₂₆O₆
CFN98363	Secoisolariciresinol	29388-59-8	362.4	C₂₀H₂₆O₆
CFN96682	Secoisolariciresinol monoglucoside	63320-67-2	524.56	C₂₆H₃₆O₁₁
CFN99722	Secoisolariciresinol Diglucoside	148244-82-0	686.71	C₃₂H₄₆O₁₆
CFN95975	Cyclolignanyingoside A	N/A	654.7	C₃₁H₄₂O₁₅
CFN95601	Secoisolariciresinol 9,9'-diacetate	848844-79-1	446.5	C₂₄H₃₀O₈
CFN98956	9,9'-Di-O-(E)-feruloylsecoisolariciresinol	56973-66-1	714.8	C₄₀H₄₂O₁₂
CFN91423	Dihydrocubebin	24563-03-9	358.4	C₂₀H₂₂O₆