Demethylcarolignan E | CAS:873694-46-3

Demethylcarolignan E

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Description:

Demethylcarolignan E is a natural product from Hibiscus taiwanensis.

In vitro:

Bioorg Med Chem. 2004 May 1;12(9):2193-7.

Cytotoxicity of phenylpropanoid esters from the stems of Hibiscus taiwanensis.[Pubmed: 15080919]

METHODS AND RESULTS:
The separation of an extract prepared from the stems of the previously uninvestigated Hibiscus taiwanensis led to the isolation of three new phenylpropanoid esters, (7S,8S)-Demethylcarolignan E (1), hibiscuwanin A (2), hibiscuwanin B (3), in addition to eight known ones. The structures of these compounds were elucidated by spectroscopic and chemical transformation studies.
CONCLUSIONS:
In cytotoxicity evaluation of the isolates, 9,9'-O-feruloyl-(-)-secoisolaricinresinol (8) showed strong cytotoxic activity against human lung carcinoma and breast carcinoma cell lines in an in vitro cytotoxicity assay with EC(50) values of 1.8 and 3.9 microg/mL, respectively.

Demethylcarolignan E Description

Source:	The stems of Hibiscus taiwanensis.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Demethylcarolignan E
Price:
CAS No.:	873694-46-3
Catalog No.:	CFN96712
Molecular Formula:	C₃₉H₄₀O₁₃
Molecular Weight:	716.73 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The stems of Hibiscus taiwanensis.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Lignans Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.3952 mL	6.9761 mL	13.9523 mL	27.9045 mL	34.8806 mL
5 mM	0.279 mL	1.3952 mL	2.7905 mL	5.5809 mL	6.9761 mL
10 mM	0.1395 mL	0.6976 mL	1.3952 mL	2.7905 mL	3.4881 mL
50 mM	0.0279 mL	0.1395 mL	0.279 mL	0.5581 mL	0.6976 mL
100 mM	0.014 mL	0.0698 mL	0.1395 mL	0.279 mL	0.3488 mL

CFN99752	Myrislignan	171485-39-5	374.43	C₂₁H₂₆O₆
CFN92657	1-(3,4-dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol	41535-95-9	374.4	C₂₁H₂₆O₆
CFN96736	Acetylvirolin	916264-22-7	400.47	C₂₃H₂₈O₆
CFN97728	4,9,9'-Trihydroxy-3,3'-dimethoxy-8,4'-oxyneolignan	53505-68-3	362.42	C₂₀H₂₆O₆
CFN96719	erythro-Guaiacylglycerol beta-dihydroconiferyl ether	135820-77-8	378.42	C₂₀H₂₆O₇
CFN95682	4,7,9,9'-Tetrahydroxy-3,3'-dimethoxy-8,4'-oxyneolignan 7-O-beta-D-glucopyranoside	182056-97-9	540.6	C₂₆H₃₆O₁₂
CFN95730	Isodonoside II	2095793-37-4	540.6	C₂₆H₃₆O₁₂
CFN95697	threo-7,9,9'-Trihydroxy-3,3'-dimethoxy-8-O-4'-neolignan 4-O-beta-D-glucopyranoside	1009838-88-3	540.6	C₂₆H₃₆O₁₂
CFN97457	erythro-Guaiacylglycerol beta-coniferyl ether	890317-92-7	376.4	C₂₀H₂₄O₇
CFN97431	threo-Guaiacylglycerol beta-coniferyl ether	869799-76-8	376.4	C₂₀H₂₄O₇