Science | Nature | Cell | View More
Natural Products
Demethylcarolignan E
Demethylcarolignan E
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Demethylcarolignan E
Price:
CAS No.: 873694-46-3
Catalog No.: CFN96712
Molecular Formula: C39H40O13
Molecular Weight: 716.73 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The stems of Hibiscus taiwanensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Universidad de Antioquia (Colombia)
  • Deutsches Krebsforschungszentrum (Germany)
  • University of British Columbia (Canada)
  • University of Limpopo (South Africa)
  • Chinese University of Hong Kong (China)
  • Institute of Pathophysiology Me... (Austria)
  • University of Amsterdam (Netherlands)
  • Georgia Institute of Technology (USA)
  • Wroclaw Medical University (Poland)
  • Universidad de La Salle (Mexico)
  • Monash University Sunway Campus (Malaysia)
  • More...
Package
Featured Products
Inotodiol

Catalog No: CFN92367
CAS No: 35963-37-2
Price: $338/5mg
Matrine

Catalog No: CFN98835
CAS No: 519-02-8
Price: $30/20mg
Isochlorogenic acid A

Catalog No: CFN99118
CAS No: 2450-53-5
Price: $50/20mg
Sesamin

Catalog No: CFN97034
CAS No: 607-80-7
Price: $40/20mg
Strictosamide

Catalog No: CFN98237
CAS No: 23141-25-5
Price: $158/10mg
Delphinidin-3-O-rutinoside chloride

Catalog No: CFN92136
CAS No: 15674-58-5
Price: $383/5mg
Pelargonidin chloride

Catalog No: CFN92132
CAS No: 134-04-3
Price: $318/10mg
Taxiphyllin

Catalog No: CFN98070
CAS No: 21401-21-8
Price: $ /
Kukoamine B

Catalog No: CFN93216
CAS No: 164991-67-7
Price: $268/10mg
Paclitaxel

Catalog No: CFN97759
CAS No: 33069-62-4
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Demethylcarolignan E is a natural product from Hibiscus taiwanensis.
In vitro:
Bioorg Med Chem. 2004 May 1;12(9):2193-7.
Cytotoxicity of phenylpropanoid esters from the stems of Hibiscus taiwanensis.[Pubmed: 15080919]

METHODS AND RESULTS:
The separation of an extract prepared from the stems of the previously uninvestigated Hibiscus taiwanensis led to the isolation of three new phenylpropanoid esters, (7S,8S)-Demethylcarolignan E (1), hibiscuwanin A (2), hibiscuwanin B (3), in addition to eight known ones. The structures of these compounds were elucidated by spectroscopic and chemical transformation studies.
CONCLUSIONS:
In cytotoxicity evaluation of the isolates, 9,9'-O-feruloyl-(-)-secoisolaricinresinol (8) showed strong cytotoxic activity against human lung carcinoma and breast carcinoma cell lines in an in vitro cytotoxicity assay with EC(50) values of 1.8 and 3.9 microg/mL, respectively.
Demethylcarolignan E Description
Source: The stems of Hibiscus taiwanensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
New Compound 1

Catalog No: CFN95152
CAS No: N/A
Price: $398/5mg
1,2-Epoxy-10(14)-furanogermacren-6...

Catalog No: CFN95214
CAS No: 383368-24-9
Price: $318/10mg
Jacquilenin

Catalog No: CFN95434
CAS No: 7726-34-3
Price: $318/5mg
Spinacetin

Catalog No: CFN95194
CAS No: 3153-83-1
Price: $318/5mg
Dactylorhin A

Catalog No: CFN95032
CAS No: 256459-34-4
Price: $238/20mg
Elgonica dimer A

Catalog No: CFN95445
CAS No: 132210-48-1
Price: $368/5mg
Dehydrodicatechin A

Catalog No: CFN95451
CAS No: 36048-23-4
Price: $318/5mg
2',4'-Dihydroxychalcone

Catalog No: CFN95493
CAS No: 1776-30-3
Price: $318/20mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3952 mL 6.9761 mL 13.9523 mL 27.9045 mL 34.8806 mL
5 mM 0.279 mL 1.3952 mL 2.7905 mL 5.5809 mL 6.9761 mL
10 mM 0.1395 mL 0.6976 mL 1.3952 mL 2.7905 mL 3.4881 mL
50 mM 0.0279 mL 0.1395 mL 0.279 mL 0.5581 mL 0.6976 mL
100 mM 0.014 mL 0.0698 mL 0.1395 mL 0.279 mL 0.3488 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Inotodiol

Catalog No: CFN92367
CAS No: 35963-37-2
Price: $338/5mg
Matrine

Catalog No: CFN98835
CAS No: 519-02-8
Price: $30/20mg
Isochlorogenic acid A

Catalog No: CFN99118
CAS No: 2450-53-5
Price: $50/20mg
Sesamin

Catalog No: CFN97034
CAS No: 607-80-7
Price: $40/20mg
Strictosamide

Catalog No: CFN98237
CAS No: 23141-25-5
Price: $158/10mg
Delphinidin-3-O-rutinoside chloride

Catalog No: CFN92136
CAS No: 15674-58-5
Price: $383/5mg
Pelargonidin chloride

Catalog No: CFN92132
CAS No: 134-04-3
Price: $318/10mg
Taxiphyllin

Catalog No: CFN98070
CAS No: 21401-21-8
Price: $ /
Kukoamine B

Catalog No: CFN93216
CAS No: 164991-67-7
Price: $268/10mg
Paclitaxel

Catalog No: CFN97759
CAS No: 33069-62-4
Price: $30/20mg
Tags: buy Demethylcarolignan E | Demethylcarolignan E supplier | purchase Demethylcarolignan E | Demethylcarolignan E cost | Demethylcarolignan E manufacturer | order Demethylcarolignan E | Demethylcarolignan E distributor