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Deoxyflindissone
Deoxyflindissone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Deoxyflindissone
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CAS No.: 107176-31-8
Catalog No.: CFN96965
Molecular Formula: C30H46O2
Molecular Weight: 438.69 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The stems and stem bark of Cornus walteri.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Deoxyflindissone exhibits significant cytotoxic activity against the A549, SK-OV-3, SK-MEL-2, and XF498 cell lines.
In vitro:
J Nat Prod. 2011 Jan 28;74(1):54-9.
Tirucallane triterpenoids from Cornus walteri.[Pubmed: 21182258 ]

METHODS AND RESULTS:
Twelve new tirucallane triterpenoids, named cornusalterins A-L (1-12), and two known tirucallane triterpenoids, Deoxyflindissone (13) and (-)-leucophyllone (14), were isolated from a MeOH extract of stems and stem bark of Cornus walteri. The structures of the new compounds were determined by spectroscopic methods, including 1D and 2D NMR analyses.
CONCLUSIONS:
Compounds 12 and 13, possessing a tetrahydrofuran ring in the side chain, exhibited significant cytotoxic activity against the A549, SK-OV-3, SK-MEL-2, and XF498 cell lines.
Deoxyflindissone Description
Source: The stems and stem bark of Cornus walteri.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2795 mL 11.3976 mL 22.7951 mL 45.5903 mL 56.9879 mL
5 mM 0.4559 mL 2.2795 mL 4.559 mL 9.1181 mL 11.3976 mL
10 mM 0.228 mL 1.1398 mL 2.2795 mL 4.559 mL 5.6988 mL
50 mM 0.0456 mL 0.228 mL 0.4559 mL 0.9118 mL 1.1398 mL
100 mM 0.0228 mL 0.114 mL 0.228 mL 0.4559 mL 0.5699 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Diallyl disulfide

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