Dihydrooroxylin A | CAS:18956-18-8 | Manufacturer ChemFaces

Dihydrooroxylin A

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Dihydrooroxylin A has significant antifeeding activity.

In vitro:

Phytochemistry. 2004 Jul;65(14):2173-6.

Insect antifeedant compounds from Nothofagus dombeyi and N. pumilio.[Pubmed: 15279992]

METHODS AND RESULTS:
A bioassay-guided purification of the extracts of Nothofagus dombeyi and N. pumilio leaves yielded several triterpenes and flavonoids including 2-O-acetylmaslinic acid, 3-O-acetyl 20,24,25-trihydroxydammarane, and 3,20,24,25-tetrahydroxydammarane as new natural products. All the isolated compounds were assessed for antifeeding activity against the 5th instar larvae of Ctenopsteustis obliquana.
CONCLUSIONS:
12-Hydroxyoleanolic lactone and pectolinarigenin from N. dombeyi and Dihydrooroxylin A from N. pumilio, showed significant antifeeding activity.

In vivo:

Biol Pharm Bull. 1998 Dec;21(12):1251-7.

Characteristics of delayed excretion of flavonoids in human urine after administration of Shosaiko-to, a herbal medicine.[Pubmed: 9881633 ]

METHODS AND RESULTS:
Two flavanones, S-dihydrowogonin and S-Dihydrooroxylin A, were identified as the metabolites of wogonin and oroxylin A, respectively. Excretion rate-time curves of the flavonoids were divided into three types of structure-dependent absorption, i.e. (1) the fast absorption of herbal-origin aglycons, (2) the moderately-delayed absorption of aglycons derived from herbal glycosides, and (3) markedly-delayed absorption after the molecular transformation of herbal compounds. Individual excretion profiles seemed to depend on microflora activities.
CONCLUSIONS:
Two types of flavanones, S-dihydrowogonin and S-Dihydrooroxylin A, were found in a half of the volunteers, suggesting there might be two kinds of volunteers, namely, rapid and poor metabolizers of flavonoids.

Dihydrooroxylin A Description

Source:	The roots of Scutellaria baicalensis Georgi
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Dihydrooroxylin A
Price:
CAS No.:	18956-18-8
Catalog No.:	CFN92591
Molecular Formula:	C₁₆H₁₄O₅
Molecular Weight:	286.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The roots of Scutellaria baicalensis Georgi
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.4928 mL	17.4642 mL	34.9284 mL	69.8568 mL	87.321 mL
5 mM	0.6986 mL	3.4928 mL	6.9857 mL	13.9714 mL	17.4642 mL
10 mM	0.3493 mL	1.7464 mL	3.4928 mL	6.9857 mL	8.7321 mL
50 mM	0.0699 mL	0.3493 mL	0.6986 mL	1.3971 mL	1.7464 mL
100 mM	0.0349 mL	0.1746 mL	0.3493 mL	0.6986 mL	0.8732 mL

CFN94487	7-Hydroxyflavanone	6515-36-2	240.26	C₁₅H₁₂O₃
CFN98740	Pinocembrin	480-39-7	256.3	C₁₅H₁₂O₄
CFN99096	Pinocembrin 7-acetate	109592-60-1	298.3	C₁₇H₁₄O₅
CFN99211	Pinocembrin diacetate	111441-88-4	340.3	C₁₉H₁₆O₆
CFN98739	Pinostrobin	480-37-5	270.3	C₁₆H₁₄O₄
CFN98489	Alpinetin	36052-37-6	270.3	C₁₆H₁₄O₄
CFN92662	5,7-Dimethoxyflavanone	1036-72-2	284.3	C₁₇H₁₆O₄
CFN90899	(2R)-5,7-Dimethoxyflavanone	1277188-85-8	284.31	C₁₇H₁₆O₄
CFN93796	Dihydrobaicalein	35683-17-1	272.3	C₁₅H₁₂O₅
CFN92591	Dihydrooroxylin A	18956-18-8	286.3	C₁₆H₁₄O₅