Echinulin | CAS:1859-87-6 | Manufacturer ChemFaces

Echinulin

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Description:

Echinulin has toxicity in rabbits.

In vitro:

Appl Environ Microbiol. 1988 Mar;54(3):830-1.

Eurotium spp. and echinulin in feed refused by swine.[Pubmed: 3377495]

METHODS AND RESULTS:
Feed refused by swine contained a high-propagule density of Eurotium chevalieri Mangin (anamorph, Aspergillus chevalieri (Mangin) Thom and Church), Eurotium amstelodami Mangin (anamorph, Aspergillus amstelodami (Mangin Thom and Church), and Aspergillus candidus Link. Echinulin (8 micrograms/g of feed) was detected in the feed. Isolates of E. chevalieri and E. amstelodami but not A. candidus produced Echinulin on rice or cracked corn.
CONCLUSIONS:
Mice refused to drink water containing 90 micrograms of Echinulin per ml. This is the first report of the alkaloid Echinulin in feed refused by swine.

In vivo:

Toxicol Lett. 1989 Sep;48(3):235-41.

Toxicity of echinulin from Aspergillus chevalieri in rabbits.[Pubmed: 2781591]

METHODS AND RESULTS:
Rabbits were injected intraperitoneally with purified Echinulin, a product of Aspergillus chevalieri. After 2 h, the rabbits were bled and enzyme analyses were carried out on the supernates of liver homogenates and citrated plasma. Elevated levels of total plasma lactate dehydrogenase, cardiac derived isozyme, glutamic-oxaloacetic and glutamic-pyruvic transaminase activities in animals receiving toxin were observed. These levels were statistically significant compared to the vehicle control. A significant increase in liver lactate dehydrogenase of toxin-treated rabbits was also observed.
CONCLUSIONS:
Light-microscopic examination of lung and liver showed a significant degree of damage. The increase in plasma enzyme levels is indicative of damage to these organs.

Echinulin Description

Source:	From Aspergillus chevalieri.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Echinulin
Price:
CAS No.:	1859-87-6
Catalog No.:	CFN99862
Molecular Formula:	C₂₉H₃₉N₃O₂
Molecular Weight:	461.7 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	From Aspergillus chevalieri.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Toxicity Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1659 mL	10.8295 mL	21.6591 mL	43.3182 mL	54.1477 mL
5 mM	0.4332 mL	2.1659 mL	4.3318 mL	8.6636 mL	10.8295 mL
10 mM	0.2166 mL	1.083 mL	2.1659 mL	4.3318 mL	5.4148 mL
50 mM	0.0433 mL	0.2166 mL	0.4332 mL	0.8664 mL	1.083 mL
100 mM	0.0217 mL	0.1083 mL	0.2166 mL	0.4332 mL	0.5415 mL

CFN98447	Gardneramine	34274-91-4	412.5	C₂₃H₂₈N₂O₅
CFN96295	Quinamine	464-85-7	312.4	C₁₉H₂₄N₂O₂
CFN96329	Conquinamine	464-86-8	312.4	C₁₉H₂₄N₂O₂
CFN99043	Dihydrocinchonamine	10283-68-8	298.4	C₁₉H₂₆N₂O
CFN98823	Neoechinulin A	51551-29-2	323.4	C₁₉H₂₁N₃O₂
CFN99862	Echinulin	1859-87-6	461.7	C₂₉H₃₉N₃O₂
CFN96445	Voafinidine	180059-77-2	328.45	C₂₀H₂₈N₂O₂
CFN96472	Tryprostatin A	171864-80-5	381.47	C₂₂H₂₇N₃O₃