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Emiline
Emiline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Emiline
Price:
CAS No.: 36506-99-7
Catalog No.: CFN00368
Molecular Formula: C19H27NO6
Molecular Weight: 365.42 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Emilia flammea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: (±)-Emiline displays good neuroprotective effect against the corticosterone-induced apoptosis in PC12 cells.
Emiline Description
Source: The herbs of Emilia flammea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7366 mL 13.6829 mL 27.3658 mL 54.7315 mL 68.4144 mL
5 mM 0.5473 mL 2.7366 mL 5.4732 mL 10.9463 mL 13.6829 mL
10 mM 0.2737 mL 1.3683 mL 2.7366 mL 5.4732 mL 6.8414 mL
50 mM 0.0547 mL 0.2737 mL 0.5473 mL 1.0946 mL 1.3683 mL
100 mM 0.0274 mL 0.1368 mL 0.2737 mL 0.5473 mL 0.6841 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry Letters,2013,6,(3):467–470.
Emiline, a new alkaloid from the aerial parts of Emilia sonchifolia[Reference: WebLink]

METHODS AND RESULTS:
A new pyrrolidine alkaloid, Emiline (1), was isolated from the 90% EtOH extract of the aerial parts of Emilia sonchifolia. Its structure was established by various spectroscopic methods, including NMR, IR, HR-ESI-MS and X-ray crystallography. It was characterized by its skeleton derived from a bicyclo-[2.2.2]-oct-5-one ring and a pyrrolidine unit.
CONCLUSIONS:
The racemic mixture, (±)-Emiline, displayed good neuroprotective effect against the corticosterone-induced apoptosis in PC12 cells.
Phytochemistry,1987,26( 8):2430–2431.
Structure revision of emiline a pyrrolizidine alkaloid from Emilia flammea[Reference: WebLink]

METHODS AND RESULTS:
The structure of Emiline, a pyrrolizidine alkaloid isolated fromEmilia flammea has been revised from an 11-membered alkaloid to a 12-membered macrocyclic diester containing otonecine.
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