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Eriobofuran
Eriobofuran
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Eriobofuran
Price:
CAS No.: 97218-06-9
Catalog No.: CFN89145
Molecular Formula: C14H12O4
Molecular Weight: 244.24 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The fruits of Kadsura marmorata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Eriobofuran, a phytoalexin, has antimicrobialactivity, it can inhibit strongly the spore germination and germ tube growth of Pestalotia funerea, a host-pathogenic fungus of loquat tree.
Targets: Antifection
In vitro:
Journal of Pesticide Science, 1985, 10(1):101-106.
Isolation and Structural Determination of Eriobofuran, A New Dibenzofuran Phytoalexin from Leaves of Loquat, Eriobotrya japonica L[Reference: WebLink]

METHODS AND RESULTS:
An antimicrobial substance, named as Eriobofuran (Ia) was isolated from loquat leaves [Eriobotrya japonica L. (Rosaceae)] inoculated with Entomosporium eriobotryae, a host-pathogenic fungus. The structure of Eriobofuran was deduced to be 2, 4-dimethoxy-3-hydroxy-dibenzofuran by spectroscopic, chemical evidence and biosynthetic considerations. Its structure was confirmed by direct comparison with a synthetic specimen of Eriobofuran ethyl ether.
CONCLUSIONS:
Eriobofuran inhibited strongly the spore germination and germ tube growth of Pestalotia funerea, a host-pathogenic fungus of loquat tree.
Eriobofuran Description
Source: The fruits of Kadsura marmorata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

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doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0943 mL 20.4717 mL 40.9433 mL 81.8867 mL 102.3583 mL
5 mM 0.8189 mL 4.0943 mL 8.1887 mL 16.3773 mL 20.4717 mL
10 mM 0.4094 mL 2.0472 mL 4.0943 mL 8.1887 mL 10.2358 mL
50 mM 0.0819 mL 0.4094 mL 0.8189 mL 1.6377 mL 2.0472 mL
100 mM 0.0409 mL 0.2047 mL 0.4094 mL 0.8189 mL 1.0236 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhong Yao Cai. 2012 Mar;35(3):396-9.
Chemical constituents from the fruits of Kadsura marmorata.[Pubmed: 22876677]
To study the chemical constituents from the fruits of Kadsura marmorata.
METHODS AND RESULTS:
The chemical constituents were isolated and purified by chromatography on silica gel, Sephadex LH-20 column and HPLC. 9 compounds were isolated and identified as 4,5-dihydroxy-3-methoxybiphenyl (I), Eriobofuran (II), 3beta, 16beta-dihydroxy urs-2-ene (III), 2alpha, 3beta, 6beta, 23-tetrahydroxy urs-12,18-dien-28-oic acid (IV), 2alpha,3beta,23-trihydroxy urs-12-en-28-oic acid (V), rutin (VI), 2-ethylhexanoic acid (VII), 2-monolaurin (VIII), glyceryl monoricinoleate (IX) on the basis of NMR and EI-MS spectroscopic analysis.
CONCLUSIONS:
All these compounds are isolated from this genus for the first time.
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