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Eriosematin
Eriosematin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Eriosematin
Price:
CAS No.: 168010-17-1
Catalog No.: CFN93109
Molecular Formula: C19H20O4
Molecular Weight: 312.36 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Flemingia philippinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
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Biological Activity
Description: Reference standards.
In vitro:
Helvetica Chimica Acta, 2010,79(4):1147-1158.
Electrochemical Behaviour and Antioxidant Activity of Some Natural Polyphenols[Reference: WebLink]

METHODS AND RESULTS:
A number of natural polyphenols (chlorogenic acid (9), cordigol (11), cordigone (12), danthrone (1), 1,5-dihydroxy-3-methoxyxanthone (2), Eriosematin (7), flemichin D (8), frutinone A (6), mangiferin (4), quercetin (5), 1,3,6,7-tetrahydroxyxanthone (3) and verbascoside (10)) were investigated for their redox properties using cyclic voltammetry. The antioxidant properties of these compounds were also examined in two models, namely lipid peroxidation in rat synaptosomes and AAPH-mediated oxidation of serum albumin. Compounds with a catechol group (9, 4, 5, 3 and 10) were oxidized below 0.4 V and inhibited lipid peroxidation with IC50 values between 2 and 8 μM. Compounds having one or more isolated phenolic groups and showing an oxidation potential between 0.45 and 0.8 V (11, 12 and 8) inhibited lipid peroxidation with IC50 between 7 and 9 μM, except 2 (0.45 V), danthrone (0.96 V) and Eriosematin which showed no or modest antioxidant activity.
CONCLUSIONS:
Some of the investigated compounds also protected albumin from oxidation, but no structure-activity relationship was apparent, suggesting that other factors beside redox potential influence this activity.
Eriosematin Description
Source: The herbs of Flemingia philippinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2014 mL 16.0072 mL 32.0143 mL 64.0287 mL 80.0359 mL
5 mM 0.6403 mL 3.2014 mL 6.4029 mL 12.8057 mL 16.0072 mL
10 mM 0.3201 mL 1.6007 mL 3.2014 mL 6.4029 mL 8.0036 mL
50 mM 0.064 mL 0.3201 mL 0.6403 mL 1.2806 mL 1.6007 mL
100 mM 0.032 mL 0.1601 mL 0.3201 mL 0.6403 mL 0.8004 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2009 Mar;34(6):724-6.
Flavonoids from roots of Flemingia philippinensis.[Pubmed: 19624015]
To investigate the chemical constituents of the roots of Flemingia philippinensis.
METHODS AND RESULTS:
Silica gel, ODS silica gel and Sephadex LH-20 column chromatography were employed for the isolation and purification. The structures were identified on the basis of spectral data (MS, 1H-NMR and 13C-NMR) and chemical evidence. Seven compounds were isolated from the 75% ethanolic extract of the roots of F. philippinensis and identified as follows: flemiphilippinin D (1), dorsmanins I (2), osajin (3), Eriosematin (4), lupinalbin A (5), genistein (6) and 3'-O-methylorobol (7).
CONCLUSIONS:
The compounds 2, 3 and 4 were isolated from the genus Flemingia for the first time. The compounds 2 and 4 were obtained from the Flemingia philippinensis for the first time.
Madecassoside

Catalog No: CFN99913
CAS No: 34540-22-2
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Ginsenoside Compound K

Catalog No: CFN99756
CAS No: 39262-14-1
Price: $30/20mg
Brevifolincarboxylic acid

Catalog No: CFN93653
CAS No: 18490-95-4
Price: $318/20mg
Soyasaponin Ac

Catalog No: CFN90774
CAS No: 133882-74-3
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Pelargonidin chloride

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Obtusifolin

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Isoimperatorin

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Ganoderenic acid D

Catalog No: CFN90300
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beta-Eudesmol

Catalog No: CFN99537
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