Science | Nature | Cell | View More
Natural Products
Ganomycin I
Ganomycin I
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ganomycin I
Price:
CAS No.: 1191255-15-8
Catalog No.: CFN92595
Molecular Formula: C21H26O4
Molecular Weight: 342.4 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Ganoderma pfeifferi
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • National Hellenic Research Foun... (Greece)
  • Leibniz Institute of Plant Bioc... (Germany)
  • Instituto de Investigaciones Ag... (Chile)
  • Universiti Malaysia Pahang (Malaysia)
  • Kitasato University (Japan)
  • University of Fribourg (Switzerland)
  • Universidade do Porto (Portugal)
  • Universitas islam negeri Jakarta (Indonesia)
  • University of Auckland (New Zealand)
  • Stanford University (USA)
  • The Australian National University (Australia)
  • More...
Package
Featured Products
Beta-Hydroxyisovalerylshikonin

Catalog No: CFN93028
CAS No: 7415-78-3
Price: $ / mg
Malic acid

Catalog No: CFN90558
CAS No: 6915-15-7
Price: $30/20mg
Glaucine

Catalog No: CFN90408
CAS No: 475-81-0
Price: $188/20mg
Secologanic acid

Catalog No: CFN95028
CAS No: 60077-46-5
Price: $418/20mg
Delphinidin chloride

Catalog No: CFN92033
CAS No: 528-53-0
Price: $380/10mg
Procyanidin C1

Catalog No: CFN99560
CAS No: 37064-30-5
Price: $268/10mg
Obtusifolin

Catalog No: CFN90394
CAS No: 477-85-0
Price: $268/20mg
Ampelopsin

Catalog No: CFN98326
CAS No: 27200-12-0
Price: $30/20mg
Sophoraflavanone G

Catalog No: CFN92005
CAS No: 97938-30-2
Price: $138/20mg
Kaempferol 3-neohesperidoside

Catalog No: CFN98415
CAS No: 32602-81-6
Price: $/mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ganomycin I inhibits the activity of HIV-1 protease.
Targets: HIV
In vitro:
J Nat Prod. 2009 Nov;72(11):2019-23.
Inhibition of the dimerization and active site of HIV-1 protease by secondary metabolites from the Vietnamese mushroom Ganoderma colossum.[Pubmed: 19813754]

METHODS AND RESULTS:
A new farnesyl hydroquinone, Ganomycin I (1), was isolated along with ganomycin B (2) from the chloroform extract of the fruiting bodies of the Vietnamese mushroom Ganoderma colossum. These compounds inhibited HIV-1 protease with IC50 values of 7.5 and 1.0 microg/mL, respectively. Kinetic studies using Zhang-Poorman and Lineweaver plots revealed that compound 2 competitively inhibited the active site of the enzyme, whereas the tetracyclic triterpene schisanlactone A, previously isolated from the same fungus, was a dimerization inhibitor, with an IC50 value of 5.0 microg/mL.
CONCLUSIONS:
The previous findings were also confirmed by the virtual docking of both compounds with HIV-1 protease crystal structure.
Ganomycin I Description
Source: The herbs of Ganoderma pfeifferi
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Cannabiscitrin

Catalog No: CFN95278
CAS No: 520-14-9
Price: $318/5mg
Pinocembrin 7-O-(4'',6''-hexahydro...

Catalog No: CFN95462
CAS No: 1825287-22-6
Price: $318/10mg
Narirutin 4'-glucoside

Catalog No: CFN95421
CAS No: 17257-22-6
Price: $318/10mg
Glicoricone

Catalog No: CFN95063
CAS No: 161099-37-2
Price: $318/5mg
3',5-Dihydroxy-4',6,7-trimethoxyfl...

Catalog No: CFN95316
CAS No: 90850-99-0
Price: $318/5mg
Ginsenoside MC

Catalog No: CFN95232
CAS No: 175484-06-7
Price: $318/10mg
Umbelliferone 7-O-rutinoside

Catalog No: CFN95431
CAS No: 135064-04-9
Price: $318/10mg
8,8''-Bibaicalein

Catalog No: CFN95007
CAS No: 135309-02-3
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9206 mL 14.6028 mL 29.2056 mL 58.4112 mL 73.014 mL
5 mM 0.5841 mL 2.9206 mL 5.8411 mL 11.6822 mL 14.6028 mL
10 mM 0.2921 mL 1.4603 mL 2.9206 mL 5.8411 mL 7.3014 mL
50 mM 0.0584 mL 0.2921 mL 0.5841 mL 1.1682 mL 1.4603 mL
100 mM 0.0292 mL 0.146 mL 0.2921 mL 0.5841 mL 0.7301 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Beta-Hydroxyisovalerylshikonin

Catalog No: CFN93028
CAS No: 7415-78-3
Price: $ / mg
Malic acid

Catalog No: CFN90558
CAS No: 6915-15-7
Price: $30/20mg
Glaucine

Catalog No: CFN90408
CAS No: 475-81-0
Price: $188/20mg
Secologanic acid

Catalog No: CFN95028
CAS No: 60077-46-5
Price: $418/20mg
Delphinidin chloride

Catalog No: CFN92033
CAS No: 528-53-0
Price: $380/10mg
Procyanidin C1

Catalog No: CFN99560
CAS No: 37064-30-5
Price: $268/10mg
Obtusifolin

Catalog No: CFN90394
CAS No: 477-85-0
Price: $268/20mg
Ampelopsin

Catalog No: CFN98326
CAS No: 27200-12-0
Price: $30/20mg
Sophoraflavanone G

Catalog No: CFN92005
CAS No: 97938-30-2
Price: $138/20mg
Kaempferol 3-neohesperidoside

Catalog No: CFN98415
CAS No: 32602-81-6
Price: $/mg
Tags: buy Ganomycin I | Ganomycin I supplier | purchase Ganomycin I | Ganomycin I cost | Ganomycin I manufacturer | order Ganomycin I | Ganomycin I distributor