Gomisin M2 | CAS:82425-45-4 | Manufacturer ChemFaces

Gomisin M2

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Gomisin M2 is an anti-HIV agent.

Targets:

HIV

In vitro:

J Nat Prod. 2006 Dec;69(12):1697-701.

Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora.[Pubmed: 17190445]

METHODS AND RESULTS:
Bioactivity-directed fractionation of an ethanolic extract of the fruits of Schisandra rubriflora led to the isolation and identification of dibenzocyclooctadiene lignans including the new lignans rubrisandrins A (1a + 1b) and B (2) and the known lignans gomisin J (3), (+/-)-gomisin M1 (4), (+)-Gomisin M2 (5), schisanhenol (6), deoxyschisandrin, schisantherin B, schisandrin, tigloylgomisin P, gomisin O, angeloylgomisin P, and epigomisin O. Their structure and stereochemistry were determined by spectroscopic methods, including 2D-NMR techniques.
CONCLUSIONS:
Compounds 1 and 3-6 were active as anti-HIV agents. (+/-)-Gomisin M1 (4) exhibited the most potent anti-HIV activity, with EC50 and therapeutic index (TI) values of <0.65 microM and >68, respectively.

Gomisin M2 Description

Source:	The fruits of Schizandra chinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Gomisin M2
Price:
CAS No.:	82425-45-4
Catalog No.:	CFN97306
Molecular Formula:	C₂₂H₂₆O₆
Molecular Weight:	386.4 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The fruits of Schizandra chinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antiviral Compound Library Lignans Compound Library HIV Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.588 mL	12.94 mL	25.8799 mL	51.7598 mL	64.6998 mL
5 mM	0.5176 mL	2.588 mL	5.176 mL	10.352 mL	12.94 mL
10 mM	0.2588 mL	1.294 mL	2.588 mL	5.176 mL	6.47 mL
50 mM	0.0518 mL	0.2588 mL	0.5176 mL	1.0352 mL	1.294 mL
100 mM	0.0259 mL	0.1294 mL	0.2588 mL	0.5176 mL	0.647 mL

CFN92841	Schisandrin C epoxide	81345-36-0	398.4	C₂₂H₂₂O₇
CFN92278	Rubrisandrin A	919289-30-8	388.5	C₂₂H₂₈O₆
CFN99922	Schizandrin A	61281-38-7	416.51	C₂₄H₃₂O₆
CFN99012	Schisandrol A	7432-28-2	432.5	C₂₄H₃₂O₇
CFN92722	Schisanlignone A	135557-67-4	430.5	C₂₄H₃₀O₇
CFN90125	Gomisin N	69176-52-9	400.46	C₂₃H₂₈O₆
CFN99923	Schizandrin B	61281-37-6	400.47	C₂₃H₂₈O₆
CFN98990	Gomisin A	58546-54-6	416.5	C₂₃H₂₈O₇
CFN97309	R(+)-Gomisin M1	82467-50-3	386.4	C₂₂H₂₆O₆
CFN90364	Schisanhenol	69363-14-0	402.48	C₂₃H₃₀O₆