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Kansuiphorin C
Kansuiphorin C
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Kansuiphorin C
Price:
CAS No.: 133898-77-8
Catalog No.: CFN92861
Molecular Formula: C29H34O6
Molecular Weight: 478.6 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The roots of Euphorbia kansui
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Biological Activity
Description: Kansuiphorin C shows cytotoxic activity.
Kansuiphorin C Description
Source: The roots of Euphorbia kansui
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0894 mL 10.4471 mL 20.8943 mL 41.7885 mL 52.2357 mL
5 mM 0.4179 mL 2.0894 mL 4.1789 mL 8.3577 mL 10.4471 mL
10 mM 0.2089 mL 1.0447 mL 2.0894 mL 4.1789 mL 5.2236 mL
50 mM 0.0418 mL 0.2089 mL 0.4179 mL 0.8358 mL 1.0447 mL
100 mM 0.0209 mL 0.1045 mL 0.2089 mL 0.4179 mL 0.5224 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Int J Mol Sci. 2012;13(9):11247-59.
Bio-guided isolation of the cytotoxic terpenoids from the roots of Euphorbia kansui against human normal cell lines L-O2 and GES-1.[Pubmed: 23109850]

METHODS AND RESULTS:
Bioassay-guided separation of the 95% ethanol extract from the roots of E. kansui led to the isolation of 12 diverse terpenoids whose structures were identified by (1)H, (13)C NMR spectroscopy and ESI-MS as kansuinine A (1), kansuinine B (2), kansuinine C (3), Kansuiphorin C (4), 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol (5), 3-O-(2'E,4'Edecadienoyl)-20-O-acetylingenol (6), 3-O-(2'E,4'Z-decadienoyl)-20-deoxyingenol (7), 3-O-benzoyl-20-deoxyingenol (8), 5-O-benzoyl-20-deoxyingenol (9), kansenone (10), epi-kansenone (11), euphol (12).
CONCLUSIONS:
All these 12 terpernoids were evaluated in vitro for cytotoxicity on L-O2 and GES-1 cell lines.
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Kaempferide

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CAS No: 491-54-3
Price: $40/20mg
6',7'-Dihydroxybergamottin

Catalog No: CFN98307
CAS No: 264234-05-1
Price: $318/10mg
Clinopodiside A

Catalog No: CFN90479
CAS No: 142809-89-0
Price: $122/20mg
2-Hydroxycinnamic acid

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CAS No: 614-60-8
Price: $30/20mg
Astragaloside I

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Wogonin

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4-Hydroxybenzyl alcohol

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Ferruginol

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Hederacoside C

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Price: $40/20mg
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