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Lethedoside A
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Product Name Lethedoside A
Price:
CAS No.: 221289-20-9
Catalog No.: CFN98100
Molecular Formula: C24H26O11
Molecular Weight: 490.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Aquilaria sinensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Lethedoside A has inactive or weakly active against KB tumor cells.
Lethedoside A Description
Source: The herbs of Aquilaria sinensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0387 mL 10.1937 mL 20.3874 mL 40.7747 mL 50.9684 mL
5 mM 0.4077 mL 2.0387 mL 4.0775 mL 8.1549 mL 10.1937 mL
10 mM 0.2039 mL 1.0194 mL 2.0387 mL 4.0775 mL 5.0968 mL
50 mM 0.0408 mL 0.2039 mL 0.4077 mL 0.8155 mL 1.0194 mL
100 mM 0.0204 mL 0.1019 mL 0.2039 mL 0.4077 mL 0.5097 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 1999 Feb;62(2):241-3.
Five new flavone 5-O-glycosides from Lethedon tannaensis: lethedosides and lethediosides.[Pubmed: 10075750]

METHODS AND RESULTS:
Five new 7-methoxy-flavone 5-O-glycosides were isolated from a cytotoxic MeOH extract of Lethedon tannaensis, and the structures were elucidated by 2D NMR spectral analysis and by chemical methods. Lethedosides A (1), B (2), and C (3) were 5-O-glucosides of 7,3', 4'-tri-O-methylluteolin, 7,3',4',5'-tetra-O-methyltricetin, and 7,3', 4'-tri-O-methytricetin, respectively; Lethedoside A (4) and B (5) and a known compound 6 were 5-O-xylosylglucosides of 7,3', 4'-tri-O-methylluteolin, 7,3',4',5'-tetra-O-methyltricetin, and 7, 4'-di-O-methylapigenin, respectively.
CONCLUSIONS:
These flavonoids were either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.
Intermedine N-oxide

Catalog No: CFN00459
CAS No: 95462-14-9
Price: $ / mg
Gelsemine

Catalog No: CFN99001
CAS No: 509-15-9
Price: $218/20mg
Gentisic acid

Catalog No: CFN92451
CAS No: 490-79-9
Price: $40/20mg
Genistein

Catalog No: CFN98681
CAS No: 446-72-0
Price: $30/20mg
Epiberberine

Catalog No: CFN98564
CAS No: 6873-09-2
Price: $168/20mg
Dehydrocostus lactone

Catalog No: CFN98720
CAS No: 477-43-0
Price: $40/20mg
Hispidulin

Catalog No: CFN99491
CAS No: 1447-88-7
Price: $218/20mg
Dehydroabietic acid

Catalog No: CFN99822
CAS No: 1740-19-8
Price: $40/20mg
Capsaicin

Catalog No: CFN99917
CAS No: 404-86-4
Price: $50/20mg
Tectoridin

Catalog No: CFN99921
CAS No: 611-40-5
Price: $50/20mg
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