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Methylophiopogonone A
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Product Name Methylophiopogonone A
Price: $318 / 10 mg
CAS No.: 74805-90-6
Catalog No.: CFN90708
Molecular Formula: C19H16O6
Molecular Weight: 340.33 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The roots of Ophiopogon japonicus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Methylophiopogonone A is a natural product from Ophiopogon japonicus.
Methylophiopogonone A Description
Source: The roots of Ophiopogon japonicus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9383 mL 14.6916 mL 29.3832 mL 58.7665 mL 73.4581 mL
5 mM 0.5877 mL 2.9383 mL 5.8766 mL 11.7533 mL 14.6916 mL
10 mM 0.2938 mL 1.4692 mL 2.9383 mL 5.8766 mL 7.3458 mL
50 mM 0.0588 mL 0.2938 mL 0.5877 mL 1.1753 mL 1.4692 mL
100 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.5877 mL 0.7346 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemical & pharmaceutical bulletin,1993, 41(2), 391-393.
Comparative Studies on the Constituents of Ophiopogonis Tuber and Its Congeners. VII. Studies on the Homoisoflavonoids of the Subterranean Part of Ophiopogon japonicus KER-GAWLER cv. Nanus. [Reference: WebLink]

METHODS AND RESULTS:
Six known homoisoflavonoidal compounds (1-6) and three new homoisoflavonoidal compounds (7-9) were isolated from the ether-soluble fraction of the subterranean part of Ophiopogon japonicus KER-GAWLER cv. Nanus. Among them, 1,2,3,4,5 and 6 were identified as Methylophiopogonone A (1), ophiopogonone A (2), methylophiopogonanone A (3), ophiopogonanone A (4), JE-III (5) and desmethylisoophiopogonone B (6), respectively.
CONCLUSIONS:
The structures of compounds 7-9 were elucidated as 5,7,2'-trihydroxy-6-methyl-3-(3', 4'-methylenedioxybenzyl)chromone (7), 5,7,2'-trihydroxy-8-methyl-3-(3', 4'-methylenedioxybenzyl)chromone (8), and a racemate of 5-hydroxy-7,8-dimethoxy-6-methyl-3-(3', 4'-dihydroxybenzyl)chroman-4-one (9), respectively.
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