Neoprocurcumenol | CAS:102130-91-6 | Manufacturer ChemFaces

Neoprocurcumenol

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Description:

Neoprocurcumenol exerts significant toxicity on mosquito larvae.

In vitro:

Acta Trop. 2010 Jan;113(1):7-11.

Efficacy of bioactive compounds from Curcuma aromatica against mosquito larvae.[Pubmed: 19712662]

With the development of resistance to conventionally used synthetic insecticides, vector management has become acutely problematic. Hence more attention has been focused on botanicals. Therefore our present study was aimed to evaluate the efficacy of extracts from rhizomes of Curcuma aromatica against the larvae of filariasis vector mosquitoes, Culex quinquefasciatus employing standard WHO procedure at Mysore.
METHODS AND RESULTS:
The soxhlet extraction was carried out using non-polar organic solvent, petroleum ether. The efficacy of petroleum ether extract seemed to be effective with LC(50) and LC(90) values of 11.42 and 18.00 ppm respectively. Bioassay-guided fractionation through flash chromatography lead to the isolation of two larvicidal compounds namely 9-oxoNeoprocurcumenol and Neoprocurcumenol. Between the two, 9-oxoNeoprocurcumenol exerted significant toxicity (P<0.01) on mosquito larvae with LC(50) value of 5.81 ppm and LC(90) being 9.99 ppm compared to Neoprocurcumenol with 13.69 and 23.92 ppm of LC(50) and LC(90) values respectively.
CONCLUSIONS:
From the results, C. aromatica could be considered as one of the powerful candidate to bring about useful botanicals so as to prevent the resurgence of mosquito vectors.

Neoprocurcumenol Description

Source:	The rhizomes of Curcuma zedoaria
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Neoprocurcumenol
Price:
CAS No.:	102130-91-6
Catalog No.:	CFN92789
Molecular Formula:	C₁₅H₂₂O₂
Molecular Weight:	234.3 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Powder
Source:	The rhizomes of Curcuma zedoaria
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Insecticides Compound Library Sesquiterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.268 mL	21.3402 mL	42.6803 mL	85.3606 mL	106.7008 mL
5 mM	0.8536 mL	4.268 mL	8.5361 mL	17.0721 mL	21.3402 mL
10 mM	0.4268 mL	2.134 mL	4.268 mL	8.5361 mL	10.6701 mL
50 mM	0.0854 mL	0.4268 mL	0.8536 mL	1.7072 mL	2.134 mL
100 mM	0.0427 mL	0.2134 mL	0.4268 mL	0.8536 mL	1.067 mL

CFN97477	Chrysothol	911714-91-5	238.4	C₁₅H₂₆O₂
CFN97446	Alismol	87827-55-2	220.4	C₁₅H₂₄O
CFN99775	Alismoxide	87701-68-6	238.37	C₁₅H₂₆O₂
CFN96326	Guaiol	489-86-1	222.4	C₁₅H₂₆O
CFN99634	Teuclatriol	152110-17-3	256.4	C₁₅H₂₈O₃
CFN98560	Atractyloside A	126054-77-1	448.5	C₂₁H₃₆O₁₀
CFN89350	Isonardoperoxide	205248-65-3	266.33	C₁₅H₂₂O₄
CFN92654	Orobanone	78916-35-5	216.3	C₁₅H₂₀O
CFN92652	Zedoarondiol	98644-24-7	252.4	C₁₅H₂₄O₃
CFN95848	Isozedoarondiol	108887-68-9	252.4	C₁₅H₂₄O₃