Norscopolamine | CAS:4684-28-0 | Manufacturer ChemFaces

Norscopolamine

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $359.1 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Norscopolamine Description

Source:	The herbs of Atropanthe sinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Green Chemistry, 2012, 14(4):1189-1195.

One-pot oxidative N-demethylation of tropane alkaloids with hydrogen peroxide and a FeIII-TAML catalyst.[Reference: WebLink]

METHODS AND RESULTS:
The oxidative N-demethylation of tropane alkaloids to their nortropane derivatives has been investigated using H2O2 and an iron(III) tetraamido macrocycle (FeIII-TAML) catalyst. The yields of the nortropanes were found to be dependent on the amount of H2O2 used in the reaction, the catalyst loading, the nature of the organic co-solvent and the type of tropine substrate. N-Hydroxy-nortropane, N-formyl-nortropane and tropane-N-oxide derivatives were identified as by-products of the reaction.
CONCLUSIONS:
After screening various reaction conditions, the optimised conditions were applied to the N-demethylation of atropine and scopolamine at preparative scales and the desired products, noratropine and Norscopolamine, obtained following one pot reactions in good yields and high purity without the need for any chromatographic purification steps.

Product Name	Norscopolamine
Price:	$513 / 5mg
CAS No.:	4684-28-0
Catalog No.:	CFN96076
Molecular Formula:	C₁₆H₁₉NO₄
Molecular Weight:	289.3 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Atropanthe sinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.4566 mL	17.2831 mL	34.5662 mL	69.1324 mL	86.4155 mL
5 mM	0.6913 mL	3.4566 mL	6.9132 mL	13.8265 mL	17.2831 mL
10 mM	0.3457 mL	1.7283 mL	3.4566 mL	6.9132 mL	8.6415 mL
50 mM	0.0691 mL	0.3457 mL	0.6913 mL	1.3826 mL	1.7283 mL
100 mM	0.0346 mL	0.1728 mL	0.3457 mL	0.6913 mL	0.8642 mL

CFN98824	Atropine	51-55-8	289.4	C₁₇H₂₃NO₃
CFN90575	Atropine sulfate	55-48-1	387.45	C₁₇H₂₅NO₇S
CFN00475	Homatropine hydrobromide	51-56-9	356.3	C₁₆H₂₂BrNO₃
CFN96115	3alpha,6beta-Ditigloyloxytropan-7beta-ol	7159-86-6	337.4	C₁₈H₂₇NO₅
CFN98158	Scopolamine butylbromide	149-64-4	440.37	C₂₁H₃₀BrNO₄
CFN98200	Scopolamine	51-34-3	303.35	C₁₇H₂₁NO₄
CFN99709	Scopolamine hydrobromide	114-49-8	384.26	C₁₇H₂₂BrNO₄
CFN00479	Scopolamine N-oxide hydrobromide	6106-81-6	400.3	C₁₇H₂₂BrNO₅
CFN96076	Norscopolamine	4684-28-0	289.3	C₁₆H₁₉NO₄
CFN00474	Noratropine	16839-98-8	275.4	C₁₆H₂₁NO₃