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Norscopolamine
Norscopolamine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Norscopolamine
Price: $513 / 5mg
CAS No.: 4684-28-0
Catalog No.: CFN96076
Molecular Formula: C16H19NO4
Molecular Weight: 289.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Atropanthe sinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $359.1 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Libraries
Biological Activity
Description: Reference standards.
Norscopolamine Description
Source: The herbs of Atropanthe sinensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4566 mL 17.2831 mL 34.5662 mL 69.1324 mL 86.4155 mL
5 mM 0.6913 mL 3.4566 mL 6.9132 mL 13.8265 mL 17.2831 mL
10 mM 0.3457 mL 1.7283 mL 3.4566 mL 6.9132 mL 8.6415 mL
50 mM 0.0691 mL 0.3457 mL 0.6913 mL 1.3826 mL 1.7283 mL
100 mM 0.0346 mL 0.1728 mL 0.3457 mL 0.6913 mL 0.8642 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Green Chemistry, 2012, 14(4):1189-1195.
One-pot oxidative N-demethylation of tropane alkaloids with hydrogen peroxide and a FeIII-TAML catalyst.[Reference: WebLink]

METHODS AND RESULTS:
The oxidative N-demethylation of tropane alkaloids to their nortropane derivatives has been investigated using H2O2 and an iron(III) tetraamido macrocycle (FeIII-TAML) catalyst. The yields of the nortropanes were found to be dependent on the amount of H2O2 used in the reaction, the catalyst loading, the nature of the organic co-solvent and the type of tropine substrate. N-Hydroxy-nortropane, N-formyl-nortropane and tropane-N-oxide derivatives were identified as by-products of the reaction.
CONCLUSIONS:
After screening various reaction conditions, the optimised conditions were applied to the N-demethylation of atropine and scopolamine at preparative scales and the desired products, noratropine and Norscopolamine, obtained following one pot reactions in good yields and high purity without the need for any chromatographic purification steps.
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Diosmetin

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Price: $40/20mg
Bakuchalcone

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CAS No: 84575-13-3
Price: $ / mg
Umckalin

Catalog No: CFN70362
CAS No: 43053-62-9
Price: $ / mg
Citric acid

Catalog No: CFN98551
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Price: $30/20mg
Santamarine

Catalog No: CFN98667
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Price: $ /
Chebulagic acid

Catalog No: CFN92295
CAS No: 23094-71-5
Price: $ / mg
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