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Panaxyne
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Panaxyne
Price:
CAS No.: 122855-49-6
Catalog No.: CFN96202
Molecular Formula: C14H20O2
Molecular Weight: 220.3 g/mol
Purity: >=98%
Type of Compound: Lipids
Physical Desc.: Powder
Source: The roots of Panax ginseng
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
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  • Medizinische Universit?t Wien (Austria)
  • The University of Newcastle (Australia)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Leibniz-Institut für Pflanzenb... (Germany)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Panaxyne shows significant and selective cytotoxicity against SK-OV-3 with ED50 value of 1.40 microM.
In vitro:
Arch Pharm Res. 2008 Feb;31(2):154-9.
Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro.[Pubmed: 18365683]
Column chromatographic separation of the roots of cultivated-wild ginseng (Jangnoisam) led to the isolation of seven polyacetylenes (1-7).
METHODS AND RESULTS:
Their structures were determined by spectroscopic methods to be panaxynol (1), ginsenoyne-A (2), panaxydol (3), 10-methoxy heptadeca-1-ene-4, 6-dyne-3, 9-diol (4) (3R, 9R, 10R)-panaxytriol (5), Panaxyne (6), and ginsenoyne-C (7). These compounds were isolated from this source for the first time. The compounds were tested for their cytotoxic activity against four human cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro using the SRB method.
CONCLUSIONS:
Panaxydol (3) and Panaxyne (6) showed significant and selective cytotoxicity against SK-OV-3 with ED50 values 2.93 and 1.40 microM, respectively.
Panaxyne Description
Source: The roots of Panax ginseng
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.5393 mL 22.6963 mL 45.3926 mL 90.7853 mL 113.4816 mL
5 mM 0.9079 mL 4.5393 mL 9.0785 mL 18.1571 mL 22.6963 mL
10 mM 0.4539 mL 2.2696 mL 4.5393 mL 9.0785 mL 11.3482 mL
50 mM 0.0908 mL 0.4539 mL 0.9079 mL 1.8157 mL 2.2696 mL
100 mM 0.0454 mL 0.227 mL 0.4539 mL 0.9079 mL 1.1348 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Saikosaponin D

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CAS No: 20874-52-6
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beta-Rhamnocitrin

Catalog No: CFN92328
CAS No: 90-19-7
Price: $ / mg
Evodiamine

Catalog No: CFN99993
CAS No: 518-17-2
Price: $40/20mg
Humulone

Catalog No: CFN90541
CAS No: 26472-41-3
Price: $ / mg
Neochamaejasmine A

Catalog No: CFN92151
CAS No: 90411-13-5
Price: $418/5mg
Seneciphylline

Catalog No: CFN98747
CAS No: 480-81-9
Price: $238/5mg
Syringin

Catalog No: CFN99282
CAS No: 118-34-3
Price: $80/20mg
Asperglaucide

Catalog No: CFN98937
CAS No: 56121-42-7
Price: $238/5mg
Tilianin

Catalog No: CFN92764
CAS No: 4291-60-5
Price: $218/20mg
Tamarixetin

Catalog No: CFN97027
CAS No: 603-61-2
Price: $ /
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