Structure Identification: |
Chinese Traditional and Herbal Drugs, 2009, 40(10):1536-1539. | Chemical constituents in leaves of Piper laetispicum.[Reference: WebLink] | To study the chemical constituents in the leaves of Piper laetispicum. METHODS AND RESULTS: Compounds were separated and purified by silica gel column and macroporous resin. Their structures were identified on the basis of spectral methods. Sixteen compounds were isolated and identified from the leaves of P. laetispicum: (2E, 4E)-N-isobutyl-11-phenylundecadienamide (I), (2E, 4E)-N-isobutyl-15-phenylpentadecadienamide (II). laetispicine (III), (2E, 4E)-N-isobutyl-7-(3′ 4′-methylene-dioxyphenyl) heptadienamide ( IV ) , brachystamide A(V), dihydropipercide ( VI ), pipermacramide A [(2E, 4E)-N-isobutyleicosadienamide, VI], ( + )-spathulenol (VIII), d-sesamin (IX),
Piperitol (X), vitexin(XI), vitexin-2″-O-β-D-glucoside (XII), N-p-coumaroyltyramine (XIII), β-sitosterol (XIV), stigmasterol (XV), and 1-dotriacontanol (XVI). CONCLUSIONS: Compounds I and II are isolated for the first time as natural substance, compounds V , VI, and VIII are first isolated from P. laetispicum, compounds XI , XII , and XVI are obtained from the plants of Piper L. for the first time. |
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