Platyphyllenone | CAS:56973-65-0 | Manufacturer ChemFaces

Platyphyllenone

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Description:

Platyphyllenone has shown promising anti-filarial activity both in vitro and in vivo studies. It can inhibit the biosynthesis of violacein in C. violaceum CV026.

Targets:

Antifection

In vitro:

Phytomedicine. 2013 Jan 15;20(2):124-32.

Antifilarial diarylheptanoids from Alnus nepalensis leaves growing in high altitude areas of Uttarakhand, India.[Pubmed: 23219341 ]

Lymphatic filariasis continues to be a major health problem in tropical and subtropical countries. A macrofilaricidal agent capable of eliminating adult filarial parasites is urgently needed. Platyphyllenone (A), alusenone (B), hirustenone (C) and hirsutanonol (D) are important biologically active diarylheptanoids present in Alnus nepalensis.
METHODS AND RESULTS:
In the present study, we report the antifilarial activity in diarylheptanoids isolated from the leaves of Platyphyllenone. nepalensis. Out of four compounds (A-D) tested in vitro one has shown promising anti-filarial activity both in vitro and in vivo studies.

Platyphyllenone Description

Source:	The barks of Alnus japonica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Platyphyllenone
Price:
CAS No.:	56973-65-0
Catalog No.:	CFN98955
Molecular Formula:	C₁₉H₂₀O₃
Molecular Weight:	296.4 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The barks of Alnus japonica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antibacterial Compound Library Phenols Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.3738 mL	16.8691 mL	33.7382 mL	67.4764 mL	84.3455 mL
5 mM	0.6748 mL	3.3738 mL	6.7476 mL	13.4953 mL	16.8691 mL
10 mM	0.3374 mL	1.6869 mL	3.3738 mL	6.7476 mL	8.4345 mL
50 mM	0.0675 mL	0.3374 mL	0.6748 mL	1.3495 mL	1.6869 mL
100 mM	0.0337 mL	0.1687 mL	0.3374 mL	0.6748 mL	0.8435 mL

CFN98644	Platyphyllonol	41137-85-3	314.4	C₁₉H₂₂O₄
CFN96210	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one	207792-17-4	310.4	C₁₉H₁₈O₄
CFN96275	1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-diyl diacetate	1269839-26-0	416.5	C₂₃H₂₈O₇
CFN95758	1-(3-Methoxy-4-hydroxyphenyl)-3-acetoxy-5-hydroxy-7-(3,4-dihydroxy-5-methoxyphenyl)heptane	934959-67-8	434.5	C₂₃H₃₀O₈
CFN98645	Hirsutanonol	41137-86-4	346.4	C₁₉H₂₂O₆
CFN97513	Hirsutanonol 5-O-glucoside	93915-36-7	508.5	C₂₅H₃₂O₁₁
CFN96051	(3S,7S)-5,6-Dehydro-4''-de-O-methylcentrolobine	227289-51-2	296.4	C₁₉H₂₀O₃
CFN98383	Centrolobol	30359-01-4	300.4	C₁₉H₂₄O₃
CFN97928	1,7-Bis(4-hydroxyphenyl)hept-6-en-3-ol	1083195-05-4	298.4	C₁₉H₂₂O₃
CFN99088	1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one	1083200-79-6	296.4	C₁₉H₂₀O₃