Przewaquinone A | CAS:76843-23-7 | Manufacturer ChemFaces

Przewaquinone A

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $227.8 / In-stock
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Description:

Przewaquinone A has antitumor activity.

In vitro:

Chemosphere. 2013 Oct;93(6):997-1004.

Algicidal activity of Salvia miltiorrhiza Bung on Microcystis aeruginosa--towards identification of algicidal substance and determination of inhibition mechanism.[Pubmed: 23810520]

The present study was to isolate and identify a potent algicidal compound from extract of Salvia miltiorrhiza and study the potential inhibition mechanism on Microcystis aeruginosa.
METHODS AND RESULTS:
Column chromatography and bioassay-guided fractionation methods were carried out to yield neo-Przewaquinone A, which was identified by spectral analysis. The EC50 of neo-Przewaquinone A on M. aeruginosa were 4.68 mg L(-1). In addition, neo-Przewaquinone A showed relatively higher security on Chlorella pyrenoidosa and Scenedesmus obliquus, with the EC50 values of 14.78 and 10.37 mg L(-1), respectively. For the potential inhibition mechanisms, neo-Przewaquinone A caused M. aeruginosa cells morphologic damage or lysis, increased malondialdehyde content and decreased the soluble protein content, total antioxidant and superoxide dismutase activity, and significantly inhibited three photosynthesis-related genes (psaB, psbD, and rbcL).
CONCLUSIONS:
The results demonstrated the algicidal effect of neo-Przewaquinone A on M. aeruginosa and provided the possible inhibition mechanisms.

Przewaquinone A Description

Source:	The roots of Salvia miltiorrhiza
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Przewaquinone A
Price:	$338 / 5mg
CAS No.:	76843-23-7
Catalog No.:	CFN92022
Molecular Formula:	C₁₉H₁₈O₄
Molecular Weight:	310.4 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The roots of Salvia miltiorrhiza
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anticancer Compound Library Antibacterial Compound Library Anti-proliferation Compound Library Vasorelaxation Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.2216 mL	16.1082 mL	32.2165 mL	64.433 mL	80.5412 mL
5 mM	0.6443 mL	3.2216 mL	6.4433 mL	12.8866 mL	16.1082 mL
10 mM	0.3222 mL	1.6108 mL	3.2216 mL	6.4433 mL	8.0541 mL
50 mM	0.0644 mL	0.3222 mL	0.6443 mL	1.2887 mL	1.6108 mL
100 mM	0.0322 mL	0.1611 mL	0.3222 mL	0.6443 mL	0.8054 mL

CFN92165	1,2-Didehydrotanshinone IIA	119963-50-7	292.3	C₁₉H₁₆O₃
CFN98952	Tanshinone IIA	568-72-9	294.4	C₁₉H₁₈O₃
CFN90353	Hydroxytanshinone IIA	18887-18-8	310.35	C₁₉H₁₈O₄
CFN92022	Przewaquinone A	76843-23-7	310.4	C₁₉H₁₈O₄
CFN90352	3alpha-Hydroxytanshinone IIA	97399-71-8	310.35	C₁₉H₁₈O₄
CFN99820	Tanshinone IIB	17397-93-2	310.4	C₁₉H₁₈O₄
CFN92148	Methyltanshinonate	18867-19-9	338.4	C₂₀H₁₈O₅
CFN99162	Sulfotanshinone IIA Sodium	N/A	396.39	C₁₉H₁₇NaO₆S