Pseudoprotogracillin | CAS:637349-03-2

Pseudoprotogracillin

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Pseudoprotogracillin Description

Source:	The roots of Dioscorea opposita Thunb.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J Pharm Biomed Anal. 2016 Jan 5;117:372-9.

Simultaneous determination of four furostanol glycosides in rat plasma by UPLC-MS/MS and its application to PK study after oral administration of Dioscorea nipponica extracts.[Pubmed: 26433169 ]

A novel, sensitive and rapid ultra-performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) method for simultaneous quantification of four furostanol glycosides in rat plasma was established and validated.
METHODS AND RESULTS:
Ginsenoside Rb1 was used as an internal standard. Plasma samples were pretreated by liquid-liquid extraction with n-butanol and chromatographed on a C18 column (2.1×50 mm i.d., 2.6 μm) using a gradient elution program consisting of acetonitrile and water (containing 0.03% formic acid and 0.1 mM lithium acetate) at a flow rate of 0.4 mL/min. Lithium adduct ions were employed to enhance the response of the analytes in electrospray positive ionization mode and multiple reaction monitoring transitions were performed for detection. All calibration curves exhibited good linearity (r>0.999) over the range of 10-20,000 ng/mL for protodioscin and 2-4000 ng/mL for protogracillin, pseudoprotodioscin and Pseudoprotogracillin. The recoveries of the whole analytes were more than 80.3% and exhibited no severe matrix effect. Meanwhile, the intra- and inter-day precisions were all less than 10.7% and accuracies were within the range of -8.1-12.9%.
CONCLUSIONS:
The four saponins showed rapid excretion and relative high plasma concentrations when the validated method was applied to the PK study of Dioscorea nipponica extracts by intragastric administration at low, medium and high dose to rats. Moreover, the T(1/2) and AUC(0-t) of each compound turned out to behave in a dose-dependent pattern by comparing them at different dose levels.

Product Name	Pseudoprotogracillin
Price:
CAS No.:	637349-03-2
Catalog No.:	CFN93038
Molecular Formula:	C₅₁H₈₂O₂₂
Molecular Weight:	1047.2 g/mol
Purity:	>=98%
Type of Compound:	Steroids
Physical Desc.:	Powder
Source:	The roots of Dioscorea opposita Thunb.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Steroids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	0.9549 mL	4.7746 mL	9.5493 mL	19.0985 mL	23.8732 mL
5 mM	0.191 mL	0.9549 mL	1.9099 mL	3.8197 mL	4.7746 mL
10 mM	0.0955 mL	0.4775 mL	0.9549 mL	1.9099 mL	2.3873 mL
50 mM	0.0191 mL	0.0955 mL	0.191 mL	0.382 mL	0.4775 mL
100 mM	0.0095 mL	0.0477 mL	0.0955 mL	0.191 mL	0.2387 mL

CFN90705	Pseudoproto Pb	102100-46-9	1177.4	C₅₇H₉₂O₂₅
CFN90692	Officinalisinin I	57944-18-0	921.07	C₄₅H₇₆O₁₉
CFN99533	Anemarsaponin E	136565-73-6	934.03	C₄₆H₇₈O₁₉
CFN95321	(3beta,22alpha)-26-(beta-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl 2-O-(6-deoxy-alpha-mannopyranosyl)-beta-glucopyranosiduronic acid	107783-53-9	931.1	C₄₆H₇₄O₁₉
CFN95890	25S-Tupistroside E	N/A	772.9	C₃₉H₆₄O₁₅
CFN95891	25R-Tupistroside E	1448639-95-9	772.9	C₃₉H₆₄O₁₅
CFN99517	Protodioscin	55056-80-9	1049.21	C₅₁H₈₄O₂₂
CFN99585	Methyl protodioscin	54522-52-0	1063.23	C₅₂H₈₆O₂₂
CFN93008	Protodeltonin	94992-08-2	1065.21	C₅₁H₈₄O₂₃
CFN93038	Pseudoprotogracillin	637349-03-2	1047.2	C₅₁H₈₂O₂₂