(+)-Quinidine | CAS:56-54-2 | Manufacturer ChemFaces

(+)-Quinidine

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Size /Price /Stock	10 mM * 1 mL in DMSO / $10.8 / In-stock
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Description:

Quinidine, a useful antiarrhythmic compound, is usually contaminated with dihydroquinidine, a compound that itself shows potent antiarrhythmic activity.

In vitro:

Chemical Physics Letters, 1994, 222(4):403-410.

Isolation of preresonance and out-of-phase dual circular polarization Raman optical activity.[Reference: WebLink]

Quinidine, a useful antiarrhythmic compound, is usually contaminated with dihydroquinidine, a compound that itself shows potent antiarrhythmic activity.
METHODS AND RESULTS:
Complete hydrogenation of quinidine followed by conversion to dihydroquinidine derivatives was explored as a basis for eliminating the analytical problems inherent in the quality control of quinidine products and for determining their pharmacological potency and pharmacokinetic parameters without interfering impurities. Attempts to resolve the quinidine analogs, dihydrocupreidine, and its benzoyloxy ester failed with normal and reversed-phase chromatography. Ion-pairing chromatography using n-octanesulfonate in methanol:water proved successful.
CONCLUSIONS:
Using 9-hydroxy-4-methoxy acridine as internal standard, separation and quantitation of the dihydroquinidine analogs from spiked plasma samples was achieved with 92 to 95% efficiency.

(+)-Quinidine Description

Source:	The barks of Cinchona ledgeriana
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	(+)-Quinidine
Price:	$30 / 20mg
CAS No.:	56-54-2
Catalog No.:	CFN70147
Molecular Formula:	C₂₀H₂₄N₂O₂
Molecular Weight:	324.4 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The barks of Cinchona ledgeriana
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.0826 mL	15.4131 mL	30.8261 mL	61.6523 mL	77.0654 mL
5 mM	0.6165 mL	3.0826 mL	6.1652 mL	12.3305 mL	15.4131 mL
10 mM	0.3083 mL	1.5413 mL	3.0826 mL	6.1652 mL	7.7065 mL
50 mM	0.0617 mL	0.3083 mL	0.6165 mL	1.233 mL	1.5413 mL
100 mM	0.0308 mL	0.1541 mL	0.3083 mL	0.6165 mL	0.7707 mL

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CFN92969	Jaborosalactone D	19891-82-8	472.61	C₂₈H₄₀O₆
CFN95494	Isorhamnetin-3-O-rutinoside-7-O-glucoside	55481-91-9	786.7	C₃₄H₄₂O₂₁