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Quinovic acid 3-O-alpha-L-rhamnopyranoside
Quinovic acid 3-O-alpha-L-rhamnopyranoside
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Quinovic acid 3-O-alpha-L-rhamnopyranoside
Price:
CAS No.: 104055-76-7
Catalog No.: CFN99060
Molecular Formula: C36H56O9
Molecular Weight: 632.8 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The barks of Mitragyna rotundifolia
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Quinovic acid 3-O-alpha-L-rhamnopyranoside shows significant inhibitory activity against snake venom phosphodiesterase-I.
Quinovic acid 3-O-alpha-L-rhamnopyranoside Description
Source: The barks of Mitragyna rotundifolia
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5803 mL 7.9014 mL 15.8028 mL 31.6056 mL 39.507 mL
5 mM 0.3161 mL 1.5803 mL 3.1606 mL 6.3211 mL 7.9014 mL
10 mM 0.158 mL 0.7901 mL 1.5803 mL 3.1606 mL 3.9507 mL
50 mM 0.0316 mL 0.158 mL 0.3161 mL 0.6321 mL 0.7901 mL
100 mM 0.0158 mL 0.079 mL 0.158 mL 0.3161 mL 0.3951 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Kinase Assay:
Nat Prod Res. 2006 Jun;20(7):686-92.
Phosphodiesterase-I inhibitor quinovic acid glycosides from Bridelia ndellensis.[Pubmed: 16901813]

METHODS AND RESULTS:
Quinovic acid 3-O-alpha-L-rhamnopyranoside (1), quinovic acid-3-O-beta-D-fucopyranoside (2), quinovic acid-3-O-beta-D-glucopyranosyl (1 --> 4)-beta-D-fucopyranoside (3), methyl gallate (4) and ethyl gallate (5) were isolated from the ethyl acetate extract of Bridelia ndellensis barks by fractionation.
CONCLUSIONS:
Compounds 1-3 showed significant inhibitory activity against snake venom phosphodiesterase-I.
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2007 Oct;32(19):2015-8.
Quinovic acid triterpenoid saponins from bark of Mitragyna rotundifolia[Pubmed: 18161294]
To study the chemical constituents from the bark of Mitragyna rotundifolia.
METHODS AND RESULTS:
Column chromatographic techniques were applied to isolate constituents. A combination of IR, MS and NMR spectroscopy was used to identify structures of constituents. Six compounds were isolated from the n-BuOH fraction and their structures were elucidated as quinovic acid-3-O-beta-D-6-deoxy-glucopyranoside, 28-O-beta-D-glucopyranosyl ester (1), quinovic acid-27-O-alpha-L-rhamnopyranosyl ester (2), Quinovic acid 3-O-alpha-L-rhamnopyranoside (3), qunovic acid-27-O-beta-D-glucopyranosyl ester (4), quovic acid-3-O-beta-D-6-deoxy-glucopyranoside (5), qunovic acid-27-O-beta-6-deoxy-D-glucopyranosyl ester (6).
CONCLUSIONS:
Compounds 1 - 6 were isolated for the first time from the plant. Compounds 1 - 4 and 6 were isolated for the first time form the genus.
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