(R)-(-)-alpha-Phellandrene | CAS:4221-98-1

(R)-(-)-alpha-Phellandrene

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Description:

(R)-(-)-alpha-Phellandrene has antibacterial and anticandidal activity.α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage

In vitro:

Chem Biodivers . 2012 Aug;9(8):1525-1532.

Biotransformation of (-)-(R)-α-phellandrene: antimicrobial activity of its major metabolite[Pubmed: 22899613]

Terpene derivatives converted by microbial biotransformation constitute an important resource for natural pharmaceutical, fragrance, and aroma substances. In the present study, the monoterpene α-phellandrene was biotransformed by 16 different strains of microorganisms (bacteria, fungi, and yeasts). The transformation metabolites were initially screened by TLC and GC/MS, and then further characterized by NMR spectroscopic techniques. Among the six metabolites characterized, 6-hydroxypiperitone, α-phellandrene epoxide, cis-p-menth-2-en-1-ol, and carvotanacetone, which originated from (-)-(R)-α-phellandrene, are reported for the first time in this study. Additionally, the substrate and the metabolite 5-p-menthene-1,2-diol were subjected to in vitro antibacterial and anticandidal tests. The metabolite showed moderate-to-good inhibitory activities (MICs=0.125 to >4 mg/ml) against various bacteria and especially against Candida species in comparison with its substrate (-)-(R)-α-phellandrene and standard antimicrobial agents.

(R)-(-)-alpha-Phellandrene Description

Source:	The herbs of Lactuca virosa
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	(R)-(-)-alpha-Phellandrene
Price:	$30 / 20mg
CAS No.:	4221-98-1
Catalog No.:	CFN91601
Molecular Formula:	C₁₀H₁₆
Molecular Weight:	136.23 g/mol
Purity:	>=98%
Type of Compound:	Monoterpenoids
Physical Desc.:	Oil
Source:	The herbs of Lactuca virosa
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Monoterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	7.3405 mL	36.7026 mL	73.4053 mL	146.8105 mL	183.5132 mL
5 mM	1.4681 mL	7.3405 mL	14.6811 mL	29.3621 mL	36.7026 mL
10 mM	0.7341 mL	3.6703 mL	7.3405 mL	14.6811 mL	18.3513 mL
50 mM	0.1468 mL	0.7341 mL	1.4681 mL	2.9362 mL	3.6703 mL
100 mM	0.0734 mL	0.367 mL	0.7341 mL	1.4681 mL	1.8351 mL

CFN93280	Menthone	10458-14-7	154.3	C₁₀H₁₈O
CFN93286	Pulegone	89-82-7	152.2	C₁₀H₁₆O
CFN91649	(-)Isopulegone	17882-43-8	152.23	C₁₀H₁₆O
CFN98126	Isopulegol	7786-67-6	154.25	C₁₀H₁₈O
CFN98125	D-Menthol	15356-60-2	156.27	C₁₀H₂₀O
CFN98124	(1S)-(+)-Menthyl chloroformate	7635-54-3	218.72	C₁₁H₁₉ClO₂
CFN98127	(+)-Isopulegol	104870-56-6	154.25	C₁₀H₁₈O
CFN99160	DL-Menthol	15356-70-4	156.27	C₁₀H₂₀O
CFN98633	p-Menth-1-ene-3,6-diol	4031-55-4	170.3	C₁₀H₁₈O₂
CFN99604	Eucamalol	145544-91-8	168.2	C₁₀H₁₆O₂