Rheumone B | CAS:2095596-67-9 | Manufacturer ChemFaces

Rheumone B

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $318 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Rheumone B Description

Source:	The aerial parts of Rumex patientia
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Natural Product Research, 2017,31(24):2842-2849.

Phenolic constituents from Rheum nobile and their antioxidant activity.[Reference: WebLink]

Although the rhizomes of Rheum nobile Hook. f. et Thoms (Polygonaceae) are widely used in Tibetan medicine, no previous investigations regarding the biological activities and rarely chemical constituents of this plant have been reported.
METHODS AND RESULTS:
As part of an ongoing search for novel bioactive agents, a phytochemical investigation of R. nobile led to the isolation of two new compounds Rheumone B (1) and piceatannol-4'-O-β-D-(6″-O-acetyl)-glucoside (2), together with 15 known compounds by gel filtration over Sephadex LH-20 and preparative HPLC. Their structures were determined by combined spectroscopic methods. Compounds 1-10 were evaluated for their ability to scavenge 2,2-diphenyl-1-picrylhydzyl (DPPH) radical and compounds 7-10 showed relatively strong scavenging abilities with IC50 values from 2.76 μM to 11.80 μM.
CONCLUSIONS:
In conclusion, naphthalene glycosides, stilbene glycosides, flavanols, especially anthraquinones are main chemical constituents of this plant. The ability to scavenge DPPH radical of compound 8 was the highest among compounds 1-10.

Product Name	Rheumone B
Price:	$318 / 5mg
CAS No.:	2095596-67-9
Catalog No.:	CFN91851
Molecular Formula:	C₂₂H₂₄O₁₀
Molecular Weight:	448.4 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The aerial parts of Rumex patientia
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.2302 mL	11.1508 mL	22.3015 mL	44.603 mL	55.7538 mL
5 mM	0.446 mL	2.2302 mL	4.4603 mL	8.9206 mL	11.1508 mL
10 mM	0.223 mL	1.1151 mL	2.2302 mL	4.4603 mL	5.5754 mL
50 mM	0.0446 mL	0.223 mL	0.446 mL	0.8921 mL	1.1151 mL
100 mM	0.0223 mL	0.1115 mL	0.223 mL	0.446 mL	0.5575 mL

CFN99101	Daidzin	552-66-9	416.38	C₂₁H₂₀O₉
CFN70034	Ethyl salicylate	118-61-6	166.1	C₉H₁₀O₃
CFN91632	D-Sorbose	3615-56-3	180.16	C₆H₁₂O₆
CFN97303	Khellin	82-02-0	260.2	C₁₄H₁₂O₅