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Saikosaponin F
Saikosaponin F
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Saikosaponin F
Price: $198 / 20mg
CAS No.: 62687-63-2
Catalog No.: CFN90635
Molecular Formula: C48H80O17
Molecular Weight: 929.14 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Bupleurum chinense DC.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $89.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Saikosaponin F shows anti-inflammatory effect against carrageenan-induced plantar oedema in the rat.
Targets: Immunology & Inflammation related
In vitro:
Fitoterapia.1994, 65(5): 409-417.
Anti-inflammatory and hepatoprotective activity of saikosaponin f and the root extract of Bupleurum kaoi[Reference: WebLink]
A mixture of B. kaoi saponins, containing saikosaponin a, saikosaponin d and Saikosaponin F, showed anti-inflammatory effect against carrageenan-induced plantar oedema in the rat.
METHODS AND RESULTS:
The crude saponin mixture and Saikosaponin F exhibited a dose-dependent inhibiting effect. Antihepatotoxic activity was investigated in rats intoxicated with beta-D-galactosamine. Except for Saikosaponin F, administration of the other compounds significantly reduced the sGOT and sGPT levels.
CONCLUSIONS:
Pathological changes in rat hepatocytes such as inflammatory infiltration around the portal area, focal necrosis in the liver parenchyma, and hyaline degeneration, have been improved in all drugs treated groups.
Saikosaponin F Description
Source: The herbs of Bupleurum chinense DC.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0763 mL 5.3813 mL 10.7626 mL 21.5253 mL 26.9066 mL
5 mM 0.2153 mL 1.0763 mL 2.1525 mL 4.3051 mL 5.3813 mL
10 mM 0.1076 mL 0.5381 mL 1.0763 mL 2.1525 mL 2.6907 mL
50 mM 0.0215 mL 0.1076 mL 0.2153 mL 0.4305 mL 0.5381 mL
100 mM 0.0108 mL 0.0538 mL 0.1076 mL 0.2153 mL 0.2691 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN90709Buddlejasaponin IVb152580-79-5943.12C48H78O18
CFN99987Saikosaponin A20736-09-8780.99C42H68O13
CFN950852''-O-acetylsaikosaponin A102934-42-9823C44H70O14
CFN950866''-O-acetylsaikosaponin A64340-46-1823C44H70O14
CFN99989Saikosaponin D20874-52-6780.99C42H68O13
CFN98519Buddlejasaponin IV139523-30-1943.12C48H78O18
CFN99988Saikosaponin C20736-08-7927.14C48H78O17
CFN91893Ardisicrenoside B160791-12-81063.23C52H86O22
CFN90934Escin IB26339-90-21131.3C55H86O24
CFN70258Deacylgymnemic acid121686-42-8682.9C36H58O12
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