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Saikosaponin H
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Saikosaponin H
Price: $318 / 10mg
CAS No.: 91990-63-5
Catalog No.: CFN90902
Molecular Formula: C48H78O17
Molecular Weight: 927.12 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Bupleurum chinense
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison
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Size /Price /Stock 10 mM * 1 mL in DMSO / $268 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Saikosaponin H is a natural product from Bupleurum chinense.
Saikosaponin H Description
Source: The roots of Bupleurum chinense
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0786 mL 5.393 mL 10.7861 mL 21.5722 mL 26.9652 mL
5 mM 0.2157 mL 1.0786 mL 2.1572 mL 4.3144 mL 5.393 mL
10 mM 0.1079 mL 0.5393 mL 1.0786 mL 2.1572 mL 2.6965 mL
50 mM 0.0216 mL 0.1079 mL 0.2157 mL 0.4314 mL 0.5393 mL
100 mM 0.0108 mL 0.0539 mL 0.1079 mL 0.2157 mL 0.2697 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of Pharmaceutical Investigation,2008,38(1):57-61.
Determination of saikosaponin derivatives in Bupleuri Radix using HPLC-ELSD.[Reference: WebLink]

METHODS AND RESULTS:
A HPLC-ELSD method was developed to determine saikosaponin derivatives from Bupleuri Radix. Eight saikosaponins, saikosaponin c, saikosaponin i, Saikosaponin H, saikosaponin a, saikosaponin b1, saikosaponin g, saikosaponin b2, and saikosaponin d, were analyzed under optimized HPLC conditions [column: Eclipse XDB (i.d., ; mobile phase: with 0.1% COOH (v/v) for solvent A and AcCN with 0.1% COOH (v/v) for solvent B, gradient elution; flow rate: 1mL/min; injection volume: ]. Good linearity was achieved in the range from 62.5 to for each compound, and intra-day precision and accuracy at each concentration level varied between 0.05 and 5.45% and between 93.9 and 109.6%, respectively, whereas those for inter-day variations were between 0.91 to 2.73% and 94.3 to 106.1%. This HPLC-ELSD method was applied for the determination of sakosaponins from Bupleuri Radix samples, and saikosaponin a , c and d were observed as major compounds. The other saikosaponins were shown under limit of quantification level thus couldn't be quantified.
CONCLUSIONS:
The present study suggested that the introduced HPLC-ELSD method is selective and reliable, and not only saikosaponin a, but also saikosaponin c and d should be employed as the standard markers for Bupleuri Radix.
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beta-Rhamnocitrin

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Price: $ / mg
Erianin

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Lotusine

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