Sanggenone H | CAS:86450-80-8 | Manufacturer ChemFaces

Sanggenone H

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $227.8 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α and IL-1β and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages.

Targets:

TNF-α | IL Receptor | NF-kB

In vitro:

J Nat Prod. 2014 Jun 27;77(6):1297-303.

Evaluation of anti-inflammatory activity of prenylated substances isolated from Morus alba and Morus nigra.[Pubmed: 24901948 ]

Chromatographic separation of root extracts of Morus alba and M. nigra led to the identification of the 2-arylbenzofurans moracin C (1), mulberrofuran Y (2), and mulberrofuran H (3), and the prenylated flavonoids kuwanon E (4), kuwanon C (5), Sanggenone H (6), cudraflavone B (7), and morusinol (8), and the Diels-Alder adducts soroceal (9), and sanggenon E (10).
CONCLUSIONS:
The cytotoxicity and their antiphlogistic activity, determined as the attenuation of the secretion of TNF-α and IL-1β and the inhibition of NF-κB nuclear translocation in LPS-stimulated macrophages, were evaluated for compounds 1-10.

Sanggenone H Description

Source:	The roots of from Morus alba and Morus nigra.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Sanggenone H
Price:	$338 / 5mg
CAS No.:	86450-80-8
Catalog No.:	CFN90836
Molecular Formula:	C₂₀H₁₈O₆
Molecular Weight:	354.4 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The roots of from Morus alba and Morus nigra.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library TNF-α Inhibitor Library NF-kB Inhibitor Library IL Receptor Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.8217 mL	14.1084 mL	28.2167 mL	56.4334 mL	70.5418 mL
5 mM	0.5643 mL	2.8217 mL	5.6433 mL	11.2867 mL	14.1084 mL
10 mM	0.2822 mL	1.4108 mL	2.8217 mL	5.6433 mL	7.0542 mL
50 mM	0.0564 mL	0.2822 mL	0.5643 mL	1.1287 mL	1.4108 mL
100 mM	0.0282 mL	0.1411 mL	0.2822 mL	0.5643 mL	0.7054 mL

CFN96525	Euchrestaflavanone B	87402-91-3	424.49	C₂₅H₂₈O₆
CFN96521	Maackiaflavanone	156162-10-6	438.51	C₂₆H₃₀O₆
CFN96511	Abyssinone V	77263-11-7	408.49	C₂₅H₂₈O₅
CFN94881	(-)-Sophoranone	23057-55-8	460.6	C₃₀H₃₆O₄
CFN96529	5-Hydroxysophoranone	90686-12-7	476.61	C₃₀H₃₆O₅
CFN97893	Sanggenol P	1351931-30-0	492.6	C₃₀H₃₆O₆
CFN92415	(+/-)-Sigmoidin A	176046-04-1	424.5	C₂₅H₂₈O₆
CFN95213	Licoflavanone	119240-82-3	340.4	C₂₀H₂₀O₅
CFN97958	4'-O-Methyllicoflavanone	1038753-13-7	354.4	C₂₁H₂₂O₅
CFN92320	Kuwanon E	68401-05-8	424.5	C₂₅H₂₈O₆