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Sideroxylonal A
Sideroxylonal A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Sideroxylonal A
Price:
CAS No.: 145382-68-9
Catalog No.: CFN99601
Molecular Formula: C26H28O10
Molecular Weight: 500.5 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The branches of Eucalyptus globulus
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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Related Libraries
Biological Activity
Description: Sideroxylonal A, isolated from the benzene extract of the leaves of Eucalyptus grandis, is a highly potent repellent.
In vitro:
PLoS One. 2013;8(3):e58416.
Chemical variation in a dominant tree species: population divergence, selection and genetic stability across environments.[Pubmed: 23526981]

METHODS AND RESULTS:
Significant genetic variation in the expression of many PSMs resides both among and within populations of E. globulus with moderate (e.g., Sideroxylonal A h(2)op = 0.24) to high (e.g., macrocarpal G h(2)op = 0.48) narrow sense heritabilities and high coefficients of additive genetic variation estimated for some compounds.
CONCLUSIONS:
A comparison of Qst and Fst estimates suggest that variability in some of these traits may be due to selection.
Biosci. Biotech. Biochem., 1996, 60(9):1522-3.
Potent Attachment-inhibiting and -promoting Substances for the Blue Mussel, Mytilus edulis galloprovincialis, from Two Species of Eucalyptus[Reference: WebLink]

METHODS AND RESULTS:
A highly potent repellent, Sideroxylonal A, was isolated from the benzene extract of the leaves of An attaching attractant identified as 16, 18-tritriacontandione was isolated from the leaf wax of Grandinol and 16, 18-tritriacontandione analogues were tested for attaching repellent and attractant activity in order to establish structure activity relationships.
Sideroxylonal A Description
Source: The branches of Eucalyptus globulus
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

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IF=13.903(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.998 mL 9.99 mL 19.98 mL 39.96 mL 49.95 mL
5 mM 0.3996 mL 1.998 mL 3.996 mL 7.992 mL 9.99 mL
10 mM 0.1998 mL 0.999 mL 1.998 mL 3.996 mL 4.995 mL
50 mM 0.04 mL 0.1998 mL 0.3996 mL 0.7992 mL 0.999 mL
100 mM 0.02 mL 0.0999 mL 0.1998 mL 0.3996 mL 0.4995 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 1999 Feb;62(2):324-6.
Sideroxylonal C, a new inhibitor of human plasminogen activator inhibitor type-1, from the flowers of Eucalyptus albens.[Pubmed: 10075775]

METHODS AND RESULTS:
Sideroxylonal C (3), a new phloroglucinol dimer, was isolated from the flowers of Eucalyptus albens through bioassay-guided fractionation. The structure elucidation was based on 1D and 2D NMR experiments, MS analysis, and comparison with Sideroxylonal A (1) and Sideroxylonal B (2).
CONCLUSIONS:
Sideroxylonal C inhibited human plasminogen activator inhibitor type-1 at 4.7 microM without any significant effect on human tissue plasminogen activator.
CFN92877Didemethylpseudoaspidin AA142382-28-3376.4C19H20O8
CFN90684Pseudoaspidin478-28-4460.5C25H32O8
CFN98474Albaspidin AA3570-40-9404.4 C21H24O8
CFN90252Albaspidin AP59092-91-0418.44C22H26O8
CFN99573Filixic acid ABA38226-84-5612.63C32H36O12
CFN98169Agrimol B55576-66-4682.75C37H46O12
CFN99519Dryocrassin ABBA12777-70-7820.81C43H48O16
CFN90561Gossypol303-45-7518.56C30H30O8
CFN98529Acetate gossypol12542-36-8578.61C32H34O10
CFN99601Sideroxylonal A145382-68-9500.5 C26H28O10
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