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Spartioidine
Spartioidine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Spartioidine
Price:
CAS No.: 520-59-2
Catalog No.: CFN00422
Molecular Formula: C18H23NO5
Molecular Weight: 333.38 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Senecio pterophorus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Nat Prod Commun. 2015 Jul;10(7):1179-80.
Pyrrolizidine Alkaloids in Adenostyles alliariae and A. glabra from the Austrian Alps.[Pubmed: 26411004]
The alkaloid content of Adenostyles alliariae and A. glabra (Asteraceae) has been evaluated.
METHODS AND RESULTS:
Both species contain toxic macrocyclic unsaturated pyrrolizidine alkaloids with seneciphylline as the main compound accounting for more than 90% of the alkaloid fraction in all above ground plant parts. Further alkaloids were Spartioidine, acetyl-senciphylline and senecionine. Inflorescences showed the highest alkaloid contents with 21.1 and 13.4 mg/g in A. alliariae and A. glabra, respectively. Stems and leaves had 2-3 times lower contents.
CONCLUSIONS:
Therefore, these Adenostyles species must be considered as highly toxic plants.
Spartioidine Description
Source: The herbs of Senecio pterophorus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9996 mL 14.9979 mL 29.9958 mL 59.9916 mL 74.9895 mL
5 mM 0.5999 mL 2.9996 mL 5.9992 mL 11.9983 mL 14.9979 mL
10 mM 0.3 mL 1.4998 mL 2.9996 mL 5.9992 mL 7.499 mL
50 mM 0.06 mL 0.3 mL 0.5999 mL 1.1998 mL 1.4998 mL
100 mM 0.03 mL 0.15 mL 0.3 mL 0.5999 mL 0.7499 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry,1993,34(6):1629–1631.
A re-investigation of the alkaloids of Senecio pterophorus[Reference: WebLink]

METHODS AND RESULTS:
The known pyrrolizidine alkaloids seneciphylline, Spartioidine, acetylseneciphylline, senecionine, and rosmarinine have been isolated from Senecio pterophorus along with a new alkaloid, for which the name isorosmarinine is proposed.
Fitoterapia. 2002 Apr;73(2):171-3.
Alkaloids from Senecio aquaticus.[Pubmed: 11978435]
Erucifoline (1) and 9-angeloylhastanecine (2) were isolated from the aerial parts of Senecio aquaticus.
METHODS AND RESULTS:
Five other pyrrolizidine alkaloids were tentatively identified by GC/MS analysis: jacobine; seneciphylline; Spartioidine; jacozine; and senecionine.
CFN00363Crotafoline38494-87-0351.40C18H25NO6
CFN00378Ligularine34429-54-4381.4C19H27NO7
CFN00408Isatidine15503-86-3367.40C18H25NO7
CFN00418Senecionine N-oxide13268-67-2351.17C18H25NO6
CFN00420Seneciphyllinine90341-45-0375.42C20H25NO6
CFN00421Riddelline23246-96-0349.38C18H23NO6
CFN00469Riddelline N-oxide75056-11-0365.4C18H23NO7
CFN00422Spartioidine520-59-2333.38C18H23NO5
CFN0047818-HydroxyspartioidineN/A349.4C18H23NO6
CFN00424Senkirkine2318-18-5365.42C19H27NO6
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