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Stigmast-4-ene-3,6-diol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Stigmast-4-ene-3,6-diol
Price:
CAS No.: 113626-76-9
Catalog No.: CFN99234
Molecular Formula: C29H50O2
Molecular Weight: 430.7 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The barks of Ailanthus altissima
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Stigmast-4-ene-3beta,6beta-diol possesses marked inhibitory activity against 12-O- -tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
In vivo:
Biol. Pharm.Bull.,1995,18(11):1617-9.
Inhibitory effect of some oxygenated stigmastane-type sterols on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice.[Pubmed: 8593493]

METHODS AND RESULTS:
The oxygenated stigmastane-type sterols stigmastane-3 beta, 6 alpha-diol, stigmastane-3 beta, 6 beta-diol(Stigmast-4-ene-3,6-diol ), 7 alpha-hydroxysitosterol and its diacetyl derivative, 7 beta-hydroxysitosterol and its diacetyl derivative, 7-oxositosterol, 4 beta-hydroxysitosterol, and stigmast-4-ene-3 beta, 6 beta-diol were evaluated with respect to their anti-inflammatory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
CONCLUSIONS:
All of the sterols, with the exception of 7 alpha-hydroxysitosterol and its diacetyl derivative, were found to possess marked inhibitory activity. The 50% inhibitory dose of these compounds for TPA-inflammation (1 microgram) was 0.5--1.0 mg/ear.
Stigmast-4-ene-3,6-diol Description
Source: The barks of Ailanthus altissima
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3218 mL 11.609 mL 23.218 mL 46.436 mL 58.045 mL
5 mM 0.4644 mL 2.3218 mL 4.6436 mL 9.2872 mL 11.609 mL
10 mM 0.2322 mL 1.1609 mL 2.3218 mL 4.6436 mL 5.8045 mL
50 mM 0.0464 mL 0.2322 mL 0.4644 mL 0.9287 mL 1.1609 mL
100 mM 0.0232 mL 0.1161 mL 0.2322 mL 0.4644 mL 0.5805 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Price: $238/20mg
Panaxadiol

Catalog No: CFN99981
CAS No: 19666-76-3
Price: $40/20mg
8-Gingerol

Catalog No: CFN99131
CAS No: 23513-08-8
Price: $118/20mg
Lupenone

Catalog No: CFN99681
CAS No: 1617-70-5
Price: $178/20mg
Albiflorin

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CAS No: 39011-90-0
Price: $50/20mg
Colchicine

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Alisol A 24-acetate

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