Structure Identification: |
Zhongguo Zhong Yao Za Zhi. 2012 Apr;37(7):951-5. | Triterpene compounds from Cirsium setosum.[Pubmed: 22792796] | To investigate chemical constituents contained in cytotoxic petroleum ether extractive fractions from ethanol extracts of Cirsium setosum. METHODS AND RESULTS:
The constituents were separated and purified by a combination of various chromatographic methods including silica gel, Sephadex LH-20, and preparative HPLC. Structures of the isolates were elucidated by spectroscopic methods including 1D, 2D NMR and MS methods. The compound structures were also determined by reference to literature. CONCLUSIONS: Twelve compounds were separated from the petroleum ether fraction of ethanolic extract and elucidated as lupenyl acetate (1), lupeol (2), lupenone (3), beta-amyrin (4), psi-taraxasterol (5), psi-taraxasteryl acetate (6), taraxasteryl acetate (7), marsformoxide B (8), alpha-amyrenone (9), beta-amyrenone (10), Taraxasterone (11) and psi-Taraxasterone (12).
Of them, compounds 3, 5, 7-12 were separated from this genus for the first time. |
|