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Tasumatrol L
Tasumatrol L
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Tasumatrol L
Price:
CAS No.: 847835-17-0
Catalog No.: CFN96647
Molecular Formula: C36H44O15
Molecular Weight: 716.73 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The leaves and twigs of Taxus sumatrana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Biological Activity
Description: Tasumatrol L is a natural product from Taxus sumatrana.
Tasumatrol L Description
Source: The leaves and twigs of Taxus sumatrana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3952 mL 6.9761 mL 13.9523 mL 27.9045 mL 34.8806 mL
5 mM 0.279 mL 1.3952 mL 2.7905 mL 5.5809 mL 6.9761 mL
10 mM 0.1395 mL 0.6976 mL 1.3952 mL 2.7905 mL 3.4881 mL
50 mM 0.0279 mL 0.1395 mL 0.279 mL 0.5581 mL 0.6976 mL
100 mM 0.014 mL 0.0698 mL 0.1395 mL 0.279 mL 0.3488 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron, 2005, 61(5):1345-1352.
Novel taxane diterpenes from Taxus sumatrana with the first C-21 taxane ester.[Reference: WebLink]

METHODS AND RESULTS:
Phytochemical investigation of the taxane diterpenes content of an acetone extract of the leaves and twigs of Taxus sumatrana (Taxaceae) has resulted in the isolation of five new taxane diterpenes esters, tasumatrol H, tasumatrol I, tasumatrol J, tasumatrol K, Tasumatrol L (1–5) together with 13 known taxanes (11–23). Compound 5 is the first 21-carbon taxane ester to be isolated from a natural source. The structures of these taxanes as well as their derivatives were established on the basis of spectral analyses, especially MS as well as 1-and 2D NMR.
CONCLUSIONS:
Compounds 2 and 4 showed significant activity against human liver carcinoma (Hepa59T/VGH), human large cell carcinoma of the lungs (NCI), human cervical epitheloid carcinoma (Hela), human colon adenocarcinoma (DLD-1) and human medulloblastoma (Med) cell lines.
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1,1,1-Kestopentaose

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Neoandrographolide

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Price: $60/20mg
Myrrhone

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Price: $388/5mg
Lotusine

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Price: $218/10mg
Caffeoyl alcohol

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L-Phenylalanine

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3,9-Dihydroxypterocarpan

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