Tetramethylcurcumin | CAS:52328-97-9 | Manufacturer ChemFaces

Tetramethylcurcumin

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Tetramethylcurcumin Description

Source:	The rhizomes of Curcuma rcenyujin
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Feb 15;949-950:70-8.

A high-throughput quantification method of curcuminoids and curcumin metabolites in human plasma via high-performance liquid chromatography/tandem mass spectrometry.[Reference: WebLink]

METHODS AND RESULTS:
Recently, we characterized the mass spectra of curcumin, its two synthetic analogs Tetramethylcurcumin (TMC) and dimethylcyclohexyl curcumin (DMCHC), and its two metabolites tetrahydrocurcumin (THC) and curcumin O-glucuronide (COG) under a positive ion mode on a Thermo TSQ Quantum triple quadrupole mass spectrometer [9,10].
CONCLUSIONS:
The protonated molecular ions are the predominant ions in their respective mass spectra; the major fragmentation pathway for curcumin, THC, TMC, and DMCHC is the cleavage of the heptenoid chain between the 3rd and the 4th carbon atoms (Scheme 1) [9]; and the major fragmentation for COG is glycosidic cleavage (Scheme 1) [10]. Two analytic methods for quantification of curcuminoids and COG [10] were established in both mouse and human plasma under a positive mode.

Product Name	Tetramethylcurcumin
Price:
CAS No.:	52328-97-9
Catalog No.:	CFN90605
Molecular Formula:	C₂₅H₂₈O₆
Molecular Weight:	424.49 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The rhizomes of Curcuma rcenyujin
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3558 mL	11.7788 mL	23.5577 mL	47.1154 mL	58.8942 mL
5 mM	0.4712 mL	2.3558 mL	4.7115 mL	9.4231 mL	11.7788 mL
10 mM	0.2356 mL	1.1779 mL	2.3558 mL	4.7115 mL	5.8894 mL
50 mM	0.0471 mL	0.2356 mL	0.4712 mL	0.9423 mL	1.1779 mL
100 mM	0.0236 mL	0.1178 mL	0.2356 mL	0.4712 mL	0.5889 mL

CFN89281	4'-O-Methylnyasol	79004-25-4	266.34	C₁₈H₁₈O₂
CFN99213	Nyasicol	111518-95-7	316.3	C₁₇H₁₆O₆
CFN96568	Nyasicol 1,2-acetonide	1432057-64-1	356.37	C₂₀H₂₀O₆
CFN99212	Nyasicoside	111518-94-6	478.5	C₂₃H₂₆O₁₁
CFN95110	Pilosidine	229971-57-7	478.5	C₂₃H₂₆O₁₁
CFN90584	Octahydrocurcumin	36062-07-4	376.44	C₂₁H₂₈O₆
CFN97749	Hexahydrocurcumin	36062-05-2	374.43	C₂₁H₂₆O₆
CFN90583	Tetrahydrocurcumin	36062-04-1	372.41	C₂₁H₂₄O₆
CFN99185	Demethoxycurcumin	22608-11-3	338.35	C₂₀H₁₈O₅
CFN99186	Bisdemethoxycurcumin	33171-05-0	308.33	C₁₉H₁₆O₄