Tribuloside | CAS:22153-44-2 | Manufacturer ChemFaces

Tribuloside

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Tribuloside has 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, it can improve behavior and BrdU immunoreactive cells of depression model rats and possess antidepressant effect. Tribuloside exhibits antimycobacterial activity against the non-pathogenic Mycobacterium species Mycobacterium madagascariense and Mycobacterium indicus pranii, with a minimum inhibitory concentration (MIC) 5.0 mg/mL.

Targets:

Antifection

In vitro:

Nat Prod Res. 2014;28(6):351-8.

A new cinnamoylglycoflavonoid, antimycobacterial and antioxidant constituents from Heritiera littoralis leaf extracts.[Pubmed: 24443810]

A new cinnamolyglycoflavonoid 3-cinnamoylTribuloside (1), its precursor Tribuloside and two known flavonoid glycosides afzelin and astilbin were isolated from Heritiera littoralis Dryand (Sterculiaceae) ethanolic leaf extract.
METHODS AND RESULTS:
The dichloromethane leaf extract afforded two known pentacyclic triterpenoids, 3β-taraxerol and friedelin. Extracts and compounds isolated therefrom, with the exception of 3β-taraxerol, exhibited antimycobacterial activity against the non-pathogenic Mycobacterium species Mycobacterium madagascariense and Mycobacterium indicus pranii, with a minimum inhibitory concentration (MIC) 5.0 mg/mL for the crude extracts and MICs in the range of 1.6-0.8 mg/mL for the pure compounds. The extracts together with 3-cinnamoylTribuloside (1), Tribuloside and astilbin exhibited 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity.
CONCLUSIONS:
The compounds that showed dual activities could be further evaluated under clinical settings for co-administration with standard anti-tuberculosis drugs.

In vivo:

Acta Chinese Medicine & Pharmacology,2008,36(3) :13-16.

Effect of tribuloside on geurogenesis in dentate gyrus of chronic stress depression rats.[Reference: WebLink]

To observe the effect of Tribuloside on behavior and geurogenesis in dentate gyrus of chronic stress depression rats.
METHODS AND RESULTS:
All rats except the control group were singly housed and exposed an unpredicted sequence of mild stressor.The behavior of rats was detected by open-field test.And geurogenesis in dentate gyrus was observed by the Bromodeoxyuridine labelling method. Compared with control group,the weight of rats in model group showed significantly decreased(41.00±11.43g).Squares crossed(17.00±9.04),rears(6.90±4.75),and grooming(4.56±1.71s)in open-field test reduced,while time of staying in central square(4.38±0.92s)and defecation(9.34±3.01)were increased.And fluoxetine or Tribuloside significantly improve behavioral disorder and BrdU immunoreactive cells(no.1 Tribuloside group 10.23±3.81;no.2Tribuloside group 10.92±2.16;fluoxetine group 11.46±2.94).
CONCLUSIONS:
Tribuloside can improve behavior and BrdU immunoreactive cells of depression model rats and possess antidepressant effect.

Tribuloside Description

Source:	The herbs of Tribulus terrestris L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Tribuloside
Price:
CAS No.:	22153-44-2
Catalog No.:	CFN93087
Molecular Formula:	C₃₀H₂₆O₁₃
Molecular Weight:	594.52 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Tribulus terrestris L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.682 mL	8.4101 mL	16.8203 mL	33.6406 mL	42.0507 mL
5 mM	0.3364 mL	1.682 mL	3.3641 mL	6.7281 mL	8.4101 mL
10 mM	0.1682 mL	0.841 mL	1.682 mL	3.3641 mL	4.2051 mL
50 mM	0.0336 mL	0.1682 mL	0.3364 mL	0.6728 mL	0.841 mL
100 mM	0.0168 mL	0.0841 mL	0.1682 mL	0.3364 mL	0.4205 mL

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CFN60093	Ribociclib (LEE011)	1211441-98-3	434.54	C₂₃H₃₀N₈O
CFN89079	1-Methoxyberberine	29133-52-6	352.38	C₂₁H₂₀NO₅
CFN98940	3-(2,4-Dihydroxyphenyl)propionic acid	5631-68-5	182.2	C₉H₁₀O₄