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Triptocalline A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Triptocalline A
Price:
CAS No.: 201534-10-3
Catalog No.: CFN96477
Molecular Formula: C28H42O4
Molecular Weight: 442.64 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Tripterygium wilfordii Hook.f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Triptocalline A shows an inhibitory effect on rat lens aldose reductase.
Triptocalline A Description
Source: The roots of Tripterygium wilfordii Hook.f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2592 mL 11.2959 mL 22.5917 mL 45.1834 mL 56.4793 mL
5 mM 0.4518 mL 2.2592 mL 4.5183 mL 9.0367 mL 11.2959 mL
10 mM 0.2259 mL 1.1296 mL 2.2592 mL 4.5183 mL 5.6479 mL
50 mM 0.0452 mL 0.2259 mL 0.4518 mL 0.9037 mL 1.1296 mL
100 mM 0.0226 mL 0.113 mL 0.2259 mL 0.4518 mL 0.5648 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 2003 Sep;66(9):1191-6.
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis.[Pubmed: 14510595 ]

METHODS AND RESULTS:
Three new friedelane-type triterpenes named salasones A (1), B (2), and C (3), a new norfriedelane-type triterpene, salaquinone A (4), and a new acylated eudesmane-type sesquiterpene, salasol A (5), were isolated from the 80% aqueous methanolic extract of the stems of Salacia chinensis collected in Thailand.
CONCLUSIONS:
Their stereostructures were elucidated on the basis of chemical and physicochemical evidence. In addition, six constituents, 3beta,22beta-dihydroxyolean-12-en-29-oic acid, tingenone, tingenine B, regeol A, Triptocalline A, and mangiferin, were found to show an inhibitory effect on rat lens aldose reductase.
Daidzin

Catalog No: CFN99101
CAS No: 552-66-9
Price: $40/20mg
Sinomenine

Catalog No: CFN99508
CAS No: 115-53-7
Price: $30/20mg
Glycerine trioleate

Catalog No: CFN90141
CAS No: 122-32-7
Price: $30/20mg
Wogonoside

Catalog No: CFN99710
CAS No: 51059-44-0
Price: $40/20mg
6',7'-Dihydroxybergamottin

Catalog No: CFN98307
CAS No: 264234-05-1
Price: $318/10mg
Isovitexin 2''-O-arabinoside

Catalog No: CFN90943
CAS No: 53382-71-1
Price: $318/10mg
1-O-Acetyl britannilactone

Catalog No: CFN90219
CAS No: 681457-46-5
Price: $338/20mg
Alisol C monoacetate

Catalog No: CFN90199
CAS No: 26575-93-9
Price: $168/20mg
Pristimerin

Catalog No: CFN90169
CAS No: 1258-84-0
Price: $128/20mg
(+)-Borneol

Catalog No: CFN70111
CAS No: 464-43-7
Price: $30/20mg
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