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Wilforlide A acetate
Wilforlide A acetate
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Wilforlide A acetate
Price: $390 / 5mg
CAS No.: 84104-80-3
Catalog No.: CFN97336
Molecular Formula: C32H48O4
Molecular Weight: 496.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Tripterygium wilfordii Hook.f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $370 / In-stock
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Wilforlide A (T1) serves as a quality control standard of Tripterygium Glycosides that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. T1 has anti-inflammatory effects.
In vitro:
Fitoterapia, 2010, 81(8):1109-1112.
Comparative study on the anti-inflammatory and immune suppressive effect of Wilforlide A.[Reference: WebLink]
Tripterygium Glycosides (TG) is effective in the treatment of patients with a variety of inflammatory and autoimmune diseases, especially rheumatoid arthritis (RA) in clinical. Wilforlide A (T1) serves as a quality control standard of TG that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. The pharmacologic actions of T1 remain to be unidentified.
METHODS AND RESULTS:
In this paper, we studied the anti-inflammatory and immune suppressive effect of T1, and compared it with Triptolide (TP), which believed to be the major active component of TG. Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose T1 has obvious anti-inflammatory effect. Colorimetric detection contents of hemolysin, carbon elimination from plasma of mice, mice delayed hypersensitivity immune, and organ index were measured.
CONCLUSIONS:
The results show that T1 has no significant immune suppressive activity, and there has a significant difference with TP and TG. Therefore, we think the content of TP also should be controlled as a supplement standard in order to ensure safe and effective medication.
Wilforlide A acetate Description
Source: The herbs of Tripterygium wilfordii Hook.f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=22.415(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0133 mL 10.0664 mL 20.1329 mL 40.2658 mL 50.3322 mL
5 mM 0.4027 mL 2.0133 mL 4.0266 mL 8.0532 mL 10.0664 mL
10 mM 0.2013 mL 1.0066 mL 2.0133 mL 4.0266 mL 5.0332 mL
50 mM 0.0403 mL 0.2013 mL 0.4027 mL 0.8053 mL 1.0066 mL
100 mM 0.0201 mL 0.1007 mL 0.2013 mL 0.4027 mL 0.5033 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN98260Bryonolic acid24480-45-3456.7 C30H48O3
CFN99152Glycyrrhetinic acid471-53-4470.64C30H46O4
CFN9774728-Hydroxy-3-oxoolean-12-en-29-oic acid381691-22-1470.69C30H46O4
CFN9948722-Hydroxy-3-oxoolean-12-en-29-oic acid144629-84-5470.7 C30H46O4
CFN972883,22-Dihydroxyolean-12-en-29-oic acid808769-54-2472.7 C30H48O4
CFN98018Triptocallic acid D201534-09-0472.7 C30H48O4
CFN96474Triptotriterpenic acid A84108-17-8472.70C30H48O4
CFN97335Wilforlide A84104-71-2454.7 C30H46O3
CFN97336Wilforlide A acetate84104-80-3496.7 C32H48O4
CFN96834Polpunonic acid33600-93-0456.71C30H48O3
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