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Yadanzioside K
Yadanzioside K
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Yadanzioside K
Price:
CAS No.: 101559-98-2
Catalog No.: CFN96420
Molecular Formula: C36H48O18
Molecular Weight: 768.76 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The seeds of Brucea javanica.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Yadanzioside K is a natural product from Brucea javanica.
Yadanzioside K Description
Source: The seeds of Brucea javanica.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3008 mL 6.504 mL 13.008 mL 26.0159 mL 32.5199 mL
5 mM 0.2602 mL 1.3008 mL 2.6016 mL 5.2032 mL 6.504 mL
10 mM 0.1301 mL 0.6504 mL 1.3008 mL 2.6016 mL 3.252 mL
50 mM 0.026 mL 0.1301 mL 0.2602 mL 0.5203 mL 0.6504 mL
100 mM 0.013 mL 0.065 mL 0.1301 mL 0.2602 mL 0.3252 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Bull. Chem. Soc. Jpn., 1986, 59(11), 3541-6.
Structures of yadanziosides K, M, N, and O, new quassinoid glycosides from Brucea javanica (L.) Merr.[Reference: WebLink]

METHODS AND RESULTS:
Four new bitter quassinoid glycosides, Yadanzioside K, yadanzioside M, yadanzioside N, and yadanzioside O were isolated from Brucea javanica (L.) MERR and their structures were determined by spectral measurement and chemical means.
CONCLUSIONS:
The aglycone of yadanzioside O was found to exhibit a significant antitumor activity against the murine P388 lymphocytic leukemia and this aglycone could be prepared from brusatol.
CFN92009Pasakbumin B138809-10-6424.4C20H24O10
CFN90771Bruceine D21499-66-1410.4C20H26O9
CFN96426Yadanziolide C95258-12-1410.41C20H26O9
CFN96427Yadanziolide B95258-13-2442.41C20H26O11
CFN96428Yadanziolide A95258-14-3426.41C20H26O10
CFN89340Bruceine E21586-90-3412.43C20H28O9
CFN96421Yadanzioside I99132-95-3642.60C29H38O16
CFN91453Yadanzioside B106387-01-3700.7C32H44O17
CFN96417Yadanzioside P79439-84-2710.72C34H46O16
CFN96419Yadanzioside L99132-97-5726.72C34H46O17
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